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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interferon-beta level
Debug Stats
  • ### Total Build Time: 69 ms 13.101 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 412 bytes
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  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 4.874 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.180 KB
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  • Reload Stats
Jax Mouse Phenotype (1)
abnormal circulating interferon-beta level MP:0008550
Definition (1)
anomaly in the amount in the blood of one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA with antiviral, antiproliferative, and immunomodulating activity
Synonyms (1)
"abnormal circulating IFN-beta level" EXACT
Parents (1)
img abnormal circulating interferon level MP:0008548
Children (2)
img increased circulating interferon-beta level MP:0008575
img decreased circulating interferon-beta level MP:0008576
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating interferon level MP:0008548
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal circulating interferon level MP:0008548
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interferon level MP:0008548
Genes (8)

Species:
human : 8
SpeciesGeneGeneIdGene NameEvidence
HumanTMEM173340061transmembrane protein 173
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
INFERRED
HumanIFNB13456interferon, beta 1, fibroblast
INFERRED
HumanADAR103adenosine deaminase, RNA-specific
img Jax MP, Pubmed Id: 19060901, MOUSE PHENOTYPE ID: MGI:1889575
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008550abnormal circulating interferon-beta level0self