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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interferon-alpha level
Debug Stats
  • ### Total Build Time: 31 ms 13.280 KB
  • CONCEPT_NAME gt=4 ms Completed: 3 ms rowSize= 414 bytes
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  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 5.079 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.181 KB
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Jax Mouse Phenotype (1)
abnormal circulating interferon-alpha level MP:0008549
Definition (1)
anomaly in the amount in the blood of one of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells that has antiviral activity and activates natural killer cells and B cells
Synonyms (1)
"abnormal circulating alpha-IFN level" EXACT
Parents (1)
img abnormal circulating interferon level MP:0008548
Children (2)
img increased circulating interferon-alpha level MP:0008573
img decreased circulating interferon-alpha level MP:0008574
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating interferon level MP:0008548
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal circulating interferon level MP:0008548
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interferon level MP:0008548
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanRSAD291543radical S-adenosyl methionine domain containing 2
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanTLR954106toll-like receptor 9
INFERRED
HumanTLR751284toll-like receptor 7
INFERRED
HumanPACSIN129993protein kinase C and casein kinase substrate in neurons 1
INFERRED
HumanPRF15551perforin 1 (pore forming protein)
INFERRED
HumanIFNB13456interferon, beta 1, fibroblast
INFERRED
HumanFLT32322fms-related tyrosine kinase 3
INFERRED
HumanADAR103adenosine deaminase, RNA-specific
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008549abnormal circulating interferon-alpha level0self