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Details
Link-It Detail - Jax Mouse Phenotype - increased spleen germinal center number
Debug Stats
  • ### Total Build Time: 258 ms 19.140 KB
  • CONCEPT_NAME gt=2 ms Completed: 1 ms rowSize= 406 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 298 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 184 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 597 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 2.947 KB
  • CONCEPT_RELATIONSHIPS gt=204 ms Completed: 204 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=43 ms Completed: 43 ms rowSize= 13.413 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased spleen germinal center number MP:0008481
Definition (1)
greater number of spleen secondary B follicles where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs
Synonyms (1)
"increased spleen GC number" EXACT
Parents (1)
img abnormal spleen germinal center morphology MP:0002359
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal spleen germinal center morphology MP:0002359
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal spleen germinal center morphology MP:0002359
Genes (22)

Species:
human : 22
SpeciesGeneGeneIdGene NameEvidence
HumanGABPB2126626GA binding protein transcription factor, beta subunit 2
Click here to display 29 evidence detail records.
HumanFCAMR83953Fc receptor, IgA, IgM, high affinity
Click here to display 29 evidence detail records.
HumanBANK155024B-cell scaffold protein with ankyrin repeats 1
Click here to display 29 evidence detail records.
HumanLAT27040linker for activation of T cells
Click here to display 29 evidence detail records.
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Click here to display 29 evidence detail records.
HumanIKZF322806IKAROS family zinc finger 3 (Aiolos)
Click here to display 29 evidence detail records.
HumanTRAF3IP210758TRAF3 interacting protein 2
Click here to display 29 evidence detail records.
HumanTCIRG110312T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
Click here to display 29 evidence detail records.
HumanTNFSF138741tumor necrosis factor (ligand) superfamily, member 13
Click here to display 29 evidence detail records.
HumanBECN18678beclin 1, autophagy related
Click here to display 29 evidence detail records.
HumanBHLHE408553basic helix-loop-helix family, member e40
Click here to display 29 evidence detail records.
HumanTYROBP7305TYRO protein tyrosine kinase binding protein
Click here to display 29 evidence detail records.
HumanSTIM16786stromal interaction molecule 1
Click here to display 29 evidence detail records.
HumanPRKCD5580protein kinase C, delta
Click here to display 29 evidence detail records.
HumanMAD2L14085MAD2 mitotic arrest deficient-like 1 (yeast)
Click here to display 29 evidence detail records.
HumanIL17A3605interleukin 17A
Click here to display 29 evidence detail records.
HumanTNFRSF93604tumor necrosis factor receptor superfamily, member 9
Click here to display 29 evidence detail records.
HumanESR12099estrogen receptor 1
Click here to display 29 evidence detail records.
HumanCD19930CD19 molecule
Click here to display 29 evidence detail records.
HumanC5AR1728complement component 5a receptor 1
Click here to display 29 evidence detail records.
HumanC4B721complement component 4B (Chido blood group)
Click here to display 29 evidence detail records.
HumanC4A720complement component 4A (Rodgers blood group)
Click here to display 29 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008481increased spleen germinal center number0self