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Details
Link-It Detail - Jax Mouse Phenotype - abnormal macrophage derived foam cell morphology
Debug Stats
  • ### Total Build Time: 23 ms 35.857 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 424 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 313 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.026 KB
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 602 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 9.641 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=6 ms Completed: 6 ms rowSize= 22.553 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.186 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal macrophage derived foam cell morphology MP:0008243
Definition (1)
any structural anomaly of a type of macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions
Parents (2)
img abnormal macrophage morphology MP:0002446
img abnormal foam cell morphology MP:0009840
Children (1)
img increased macrophage derived foam cell number MP:0004778
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img cellular phenotype MP:00053845img abnormal foam cell morphology MP:0009840
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanGPR116221395G protein-coupled receptor 116
INFERRED
HumanPLA2G1523659phospholipase A2, group XV
INFERRED
HumanNR1H310062nuclear receptor subfamily 1, group H, member 3
INFERRED
HumanABCG19619ATP-binding cassette, sub-family G (WHITE), member 1
INFERRED
HumanMAPKAPK29261mitogen-activated protein kinase-activated protein kinase 2
img Jax MP, Pubmed Id: 10772649, MOUSE PHENOTYPE ID: MGI:107899
img Jax MP, Pubmed Id: 18326085, MOUSE PHENOTYPE ID: MGI:103177
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
img Jax MP, Pubmed Id: 23383297, MOUSE PHENOTYPE ID: MGI:103562
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
HumanSMPD16609sphingomyelin phosphodiesterase 1, acid lysosomal
INFERRED
HumanCX3CL16376chemokine (C-X3-C motif) ligand 1
INFERRED
HumanMAPK95601mitogen-activated protein kinase 9
INFERRED
HumanNPC14864Niemann-Pick disease, type C1
INFERRED
HumanMPZ4359myelin protein zero
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
img Jax MP, Pubmed Id: 10772649, MOUSE PHENOTYPE ID: MGI:107899
img Jax MP, Pubmed Id: 18326085, MOUSE PHENOTYPE ID: MGI:103177
img Jax MP, Pubmed Id: 23383297, MOUSE PHENOTYPE ID: MGI:103562
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
HumanHSD11B13290hydroxysteroid (11-beta) dehydrogenase 1
img Jax MP, Pubmed Id: 23383297, MOUSE PHENOTYPE ID: MGI:103562
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
img Jax MP, Pubmed Id: 18326085, MOUSE PHENOTYPE ID: MGI:103177
img Jax MP, Pubmed Id: 10772649, MOUSE PHENOTYPE ID: MGI:107899
HumanCD36948CD36 molecule (thrombospondin receptor)
img Jax MP, Pubmed Id: 18326085, MOUSE PHENOTYPE ID: MGI:103177
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
img Jax MP, Pubmed Id: 10772649, MOUSE PHENOTYPE ID: MGI:107899
img Jax MP, Pubmed Id: 17885219, MOUSE PHENOTYPE ID: MGI:109298
img Jax MP, Pubmed Id: 23383297, MOUSE PHENOTYPE ID: MGI:103562
HumanAPOC3345apolipoprotein C-III
INFERRED
HumanAPOA4337apolipoprotein A-IV
INFERRED
HumanAPOA1335apolipoprotein A-I
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008243abnormal macrophage derived foam cell morphology0self