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Details
Link-It Detail - Jax Mouse Phenotype - decreased susceptibility to neuronal excitotoxicity
Debug Stats
  • ### Total Build Time: 44 ms 24.386 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 430 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_GENES gt=32 ms Completed: 32 ms rowSize= 16.175 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.188 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased susceptibility to neuronal excitotoxicity MP:0008236
Definition (1)
less than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kainate-induced neuronal cell death mediated via a glutamate excitotoxic process
Synonyms (1)
"decreased susceptibility to neurotoxicity-induced cell death" EXACT
Parents (2)
img decreased physiological sensitivity to xenobiotic MP:0008874
img decreased neuron apoptosis MP:0003204
Children (1)
img decreased susceptibility to dopaminergic neuron neurotoxicity MP:0011452
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img decreased physiological sensitivity to xenobiotic MP:0008874
img mammalian phenotype MP:0000001img cellular phenotype MP:00053848img decreased neuron apoptosis MP:0003204
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036317img decreased neuron apoptosis MP:0003204
Genes (33)

Species:
human : 33
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCASP12100506742caspase 12 (gene/pseudogene)
Click here to display 31 evidence detail records.
HumanPPP1R9B84687protein phosphatase 1, regulatory subunit 9B
Click here to display 31 evidence detail records.
HumanSRR63826serine racemase
Click here to display 31 evidence detail records.
HumanRASD151655RAS, dexamethasone-induced 1
Click here to display 31 evidence detail records.
HumanFAF111124Fas (TNFRSF6) associated factor 1
INFERRED
HumanMAPK8IP19479mitogen-activated protein kinase 8 interacting protein 1
Click here to display 31 evidence detail records.
HumanAIFM19131apoptosis-inducing factor, mitochondrion-associated, 1
Click here to display 31 evidence detail records.
HumanBAG67917BCL2-associated athanogene 6
Click here to display 31 evidence detail records.
HumanTRPC57224transient receptor potential cation channel, subfamily C, member 5
Click here to display 31 evidence detail records.
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
INFERRED
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
INFERRED
HumanSURF16834surfeit 1
Click here to display 31 evidence detail records.
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
Click here to display 31 evidence detail records.
HumanSPP16696secreted phosphoprotein 1
INFERRED
HumanSNCG6623synuclein, gamma (breast cancer-specific protein 1)
INFERRED
HumanSNCA6622synuclein, alpha (non A4 component of amyloid precursor)
INFERRED
HumanSLC6A36531solute carrier family 6 (neurotransmitter transporter), member 3
INFERRED
HumanCCL136357chemokine (C-C motif) ligand 13
Click here to display 31 evidence detail records.
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Click here to display 31 evidence detail records.
HumanMAPK105602mitogen-activated protein kinase 10
Click here to display 31 evidence detail records.
HumanMAPK95601mitogen-activated protein kinase 9
INFERRED
HumanPLG5340plasminogen
Click here to display 31 evidence detail records.
HumanPLA2G4A5321phospholipase A2, group IVA (cytosolic, calcium-dependent)
INFERRED
HumanOGG149688-oxoguanine DNA glycosylase
Click here to display 31 evidence detail records.
HumanNOS14842nitric oxide synthase 1 (neuronal)
Click here to display 31 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008236decreased susceptibility to neuronal excitotoxicity0self