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Details
Link-It Detail - Jax Mouse Phenotype - abnormal follicular dendritic cell morphology
Debug Stats
  • ### Total Build Time: 19 ms 14.817 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 418 bytes
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  • CONCEPT_GENES gt=10 ms Completed: 10 ms rowSize= 9.362 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.183 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal follicular dendritic cell morphology MP:0008196
Definition (1)
any structural anomaly of a cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue; follicular dendritic cells have Fc receptors and C3b receptors, and hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response
Parents (1)
img abnormal immune system cell morphology MP:0000716
Children (2)
img increased follicular dendritic cell number MP:0008199
img decreased follicular dendritic cell number MP:0008200
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal immune system cell morphology MP:0000716
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanDOCK881704dedicator of cytokinesis 8
INFERRED
HumanCXCL1310563chemokine (C-X-C motif) ligand 13
INFERRED
HumanMAP3K149020mitogen-activated protein kinase kinase kinase 14
INFERRED
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
img Jax MP, Pubmed Id: 20457915, MOUSE PHENOTYPE ID: MGI:1314884
img Jax MP, Pubmed Id: 20457915, MOUSE PHENOTYPE ID: MGI:1314884
img Jax MP, Pubmed Id: 12055593, MOUSE PHENOTYPE ID: MGI:88140
HumanTNF7124tumor necrosis factor
INFERRED
HumanPCSK15122proprotein convertase subtilisin/kexin type 1
INFERRED
HumanLTBR4055lymphotoxin beta receptor (TNFR superfamily, member 3)
INFERRED
HumanLTB4050lymphotoxin beta (TNF superfamily, member 3)
INFERRED
HumanCXCR5643chemokine (C-X-C motif) receptor 5
INFERRED
HumanBCL3602B-cell CLL/lymphoma 3
img Jax MP, Pubmed Id: 12055593, MOUSE PHENOTYPE ID: MGI:88140
img Jax MP, Pubmed Id: 20457915, MOUSE PHENOTYPE ID: MGI:1314884
img Jax MP, Pubmed Id: 20457915, MOUSE PHENOTYPE ID: MGI:1314884
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008196abnormal follicular dendritic cell morphology0self