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Details
Link-It Detail - Jax Mouse Phenotype - absent germinal center B cells
Debug Stats
  • ### Total Build Time: 25 ms 65.179 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 388 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 442 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.027 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 16.380 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 45.641 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
absent germinal center B cells MP:0008179
Definition (1)
absence of rapidly cycling mature B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA), and are involved in T-dependent immune responses; germinal center B cells are found typically in the germinal centers of lymph nodes and spleen
Parents (2)
img decreased germinal center B cell number MP:0008178
img absent mature B cells MP:0008212
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img decreased germinal center B cell number MP:0008178
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img decreased germinal center B cell number MP:0008178
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img decreased germinal center B cell number MP:0008178
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased germinal center B cell number MP:0008178
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img decreased germinal center B cell number MP:0008178
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img decreased germinal center B cell number MP:0008178
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img immune system phenotype MP:000538713img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539714img absent mature B cells MP:0008212
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img absent mature B cells MP:0008212
Genes (7)

Species:
human : 7
SpeciesGeneGeneIdGene NameEvidence
HumanBACH260468BTB and CNC homology 1, basic leucine zipper transcription factor 2
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104798
img Jax MP, Pubmed Id: 15152264, MOUSE PHENOTYPE ID: MGI:894679
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104796
HumanBATF10538basic leucine zipper transcription factor, ATF-like
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 15152264, MOUSE PHENOTYPE ID: MGI:894679
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104796
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104798
HumanTNF7124tumor necrosis factor
img Jax MP, Pubmed Id: 15152264, MOUSE PHENOTYPE ID: MGI:894679
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104798
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104796
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
HumanMCL14170myeloid cell leukemia sequence 1 (BCL2-related)
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 15152264, MOUSE PHENOTYPE ID: MGI:894679
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104796
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104798
HumanLTB4050lymphotoxin beta (TNF superfamily, member 3)
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104796
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 15152264, MOUSE PHENOTYPE ID: MGI:894679
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104798
HumanCD40958CD40 molecule, TNF receptor superfamily member 5
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104798
img Jax MP, Pubmed Id: 15152264, MOUSE PHENOTYPE ID: MGI:894679
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104796
HumanBCL6604B-cell CLL/lymphoma 6
img Jax MP, Pubmed Id: 15152264, MOUSE PHENOTYPE ID: MGI:894679
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:107187
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104798
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 20929728, MOUSE PHENOTYPE ID: MGI:101769
img Jax MP, Pubmed Id: 20421391, MOUSE PHENOTYPE ID: MGI:1859147
img Jax MP, Pubmed Id: 23027924, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 10586051, MOUSE PHENOTYPE ID: MGI:104796
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008179absent germinal center B cells0self