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Details
Link-It Detail - Jax Mouse Phenotype - increased germinal center B cell number
Debug Stats
  • ### Total Build Time: 50 ms 27.352 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 406 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 449 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.039 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 13.735 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=36 ms Completed: 36 ms rowSize= 10.413 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
increased germinal center B cell number MP:0008177
Definition (1)
greater number of rapidly cycling mature B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA), and are involved in T-dependent immune responses; germinal center B cells are found typically in the germinal centers of lymph nodes and spleen
Parents (2)
img abnormal germinal center B cell morphology MP:0008176
img increased mature B cell number MP:0008210
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal germinal center B cell morphology MP:0008176
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal germinal center B cell morphology MP:0008176
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal germinal center B cell morphology MP:0008176
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal germinal center B cell morphology MP:0008176
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img increased mature B cell number MP:0008210
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img increased mature B cell number MP:0008210
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img increased mature B cell number MP:0008210
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img increased mature B cell number MP:0008210
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img increased mature B cell number MP:0008210
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img increased mature B cell number MP:0008210
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanAICDA57379activation-induced cytidine deaminase
Click here to display 29 evidence detail records.
HumanTRAF3IP210758TRAF3 interacting protein 2
Click here to display 29 evidence detail records.
HumanTNIP110318TNFAIP3 interacting protein 1
Click here to display 29 evidence detail records.
HumanS1PR29294sphingosine-1-phosphate receptor 2
Click here to display 29 evidence detail records.
HumanARHGEF19138Rho guanine nucleotide exchange factor (GEF) 1
Click here to display 29 evidence detail records.
HumanWAS7454Wiskott-Aldrich syndrome
Click here to display 29 evidence detail records.
HumanTYROBP7305TYRO protein tyrosine kinase binding protein
Click here to display 29 evidence detail records.
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
Click here to display 29 evidence detail records.
HumanTNFAIP37128tumor necrosis factor, alpha-induced protein 3
Click here to display 29 evidence detail records.
HumanSTIM16786stromal interaction molecule 1
Click here to display 29 evidence detail records.
HumanPTEN5728phosphatase and tensin homolog
Click here to display 29 evidence detail records.
HumanPKN15585protein kinase N1
Click here to display 29 evidence detail records.
HumanITK3702IL2-inducible T-cell kinase
Click here to display 29 evidence detail records.
HumanIL23558interleukin 2
Click here to display 29 evidence detail records.
HumanFCGR2B2213Fc fragment of IgG, low affinity IIb, receptor (CD32)
Click here to display 29 evidence detail records.
HumanCD79A973CD79a molecule, immunoglobulin-associated alpha
Click here to display 29 evidence detail records.
HumanFASLG356Fas ligand (TNF superfamily, member 6)
Click here to display 29 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008177increased germinal center B cell number0self