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Details
Link-It Detail - Jax Mouse Phenotype - podocyte foot process effacement
Debug Stats
  • ### Total Build Time: 83 ms 21.674 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 392 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 564 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 596 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 1.594 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=70 ms Completed: 70 ms rowSize= 17.242 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.170 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
podocyte foot process effacement MP:0008140
Definition (1)
a podocyte reaction to injury or damage characterized by flattening of foot processes due to gradual simplification of the interdigitating foot process; the whole podocyte looks flat due to retraction, widening, and shortening of the processes of each podocyte while the frequency of filtration slits is reduced, giving the appearance of a continuous cytoplasmic sheet covering the glomerular basement membrane
Parents (1)
img abnormal podocyte foot process morphology MP:0008059
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:000536711img abnormal podocyte foot process morphology MP:0008059
Genes (29)

Species:
human : 29
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Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGSTK1373156glutathione S-transferase kappa 1
Click here to display 66 evidence detail records.
HumanCOL18A180781collagen, type XVIII, alpha 1
Click here to display 66 evidence detail records.
HumanPDSS257107prenyl (decaprenyl) diphosphate synthase, subunit 2
Click here to display 66 evidence detail records.
HumanCRIM151232cysteine rich transmembrane BMP regulator 1 (chordin-like)
Click here to display 66 evidence detail records.
HumanRRM2B50484ribonucleotide reductase M2 B (TP53 inducible)
Click here to display 66 evidence detail records.
HumanEHD430844EH-domain containing 4
Click here to display 66 evidence detail records.
HumanGNE10020glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Click here to display 66 evidence detail records.
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
Click here to display 66 evidence detail records.
HumanWT17490Wilms tumor 1
Click here to display 66 evidence detail records.
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
Click here to display 66 evidence detail records.
HumanVEGFA7422vascular endothelial growth factor A
Click here to display 66 evidence detail records.
HumanPIK3C2A5286phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
Click here to display 66 evidence detail records.
HumanNPHS14868nephrosis 1, congenital, Finnish type (nephrin)
Click here to display 66 evidence detail records.
HumanMYO1E4643myosin IE
Click here to display 66 evidence detail records.
HumanMYH94627myosin, heavy chain 9, non-muscle
Click here to display 66 evidence detail records.
HumanMPV174358MpV17 mitochondrial inner membrane protein
Click here to display 66 evidence detail records.
HumanLMX1B4010LIM homeobox transcription factor 1, beta
Click here to display 66 evidence detail records.
HumanLAMA53911laminin, alpha 5
Click here to display 66 evidence detail records.
HumanITGA13672integrin, alpha 1
Click here to display 66 evidence detail records.
HumanHPRT13251hypoxanthine phosphoribosyltransferase 1
Click here to display 66 evidence detail records.
HumanGRM12911glutamate receptor, metabotropic 1
Click here to display 66 evidence detail records.
HumanMTOR2475mechanistic target of rapamycin (serine/threonine kinase)
Click here to display 66 evidence detail records.
HumanCOL4A51287collagen, type IV, alpha 5
Click here to display 66 evidence detail records.
HumanCOL4A31285collagen, type IV, alpha 3 (Goodpasture antigen)
Click here to display 66 evidence detail records.
HumanCD151977CD151 molecule (Raph blood group)
Click here to display 66 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008140podocyte foot process effacement0self