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Details
Link-It Detail - Jax Mouse Phenotype - abnormal Langerhans cell morphology
Debug Stats
  • ### Total Build Time: 29 ms 48.922 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 398 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 573 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 589 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 9.735 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=27 ms Completed: 27 ms rowSize= 35.763 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.173 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal Langerhans cell morphology MP:0008117
Definition (1)
any structural anomaly of a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus
Parents (1)
img abnormal myeloid dendritic cell morphology MP:0006173
Children (1)
img decreased Langerhans cell number MP:0008119
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal myeloid dendritic cell morphology MP:0006173
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal myeloid dendritic cell morphology MP:0006173
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal myeloid dendritic cell morphology MP:0006173
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal myeloid dendritic cell morphology MP:0006173
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal myeloid dendritic cell morphology MP:0006173
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal myeloid dendritic cell morphology MP:0006173
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal myeloid dendritic cell morphology MP:0006173
Genes (13)

Species:
human : 13
SpeciesGeneGeneIdGene NameEvidence
HumanIL34146433interleukin 34
INFERRED
HumanB9D280776B9 protein domain 2
INFERRED
HumanCD20750489CD207 molecule, langerin
img Jax MP, Pubmed Id: 11171393, MOUSE PHENOTYPE ID: MGI:2177412
img Jax MP, Pubmed Id: 15057277, MOUSE PHENOTYPE ID: MGI:3802582
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 19454665, MOUSE PHENOTYPE ID: MGI:105043
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 15601833, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 22411813, MOUSE PHENOTYPE ID: MGI:106653
HumanTNFSF118600tumor necrosis factor (ligand) superfamily, member 11
INFERRED
HumanTGFB17040transforming growth factor, beta 1
INFERRED
HumanMFGE84240milk fat globule-EGF factor 8 protein
INFERRED
HumanEPCAM4072epithelial cell adhesion molecule
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 15601833, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 22411813, MOUSE PHENOTYPE ID: MGI:106653
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 19454665, MOUSE PHENOTYPE ID: MGI:105043
img Jax MP, Pubmed Id: 11171393, MOUSE PHENOTYPE ID: MGI:2177412
img Jax MP, Pubmed Id: 15057277, MOUSE PHENOTYPE ID: MGI:3802582
HumanITGB63694integrin, beta 6
INFERRED
HumanCSF1R1436colony stimulating factor 1 receptor
INFERRED
HumanCSF11435colony stimulating factor 1 (macrophage)
img Jax MP, Pubmed Id: 19454665, MOUSE PHENOTYPE ID: MGI:105043
img Jax MP, Pubmed Id: 11171393, MOUSE PHENOTYPE ID: MGI:2177412
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 15057277, MOUSE PHENOTYPE ID: MGI:3802582
img Jax MP, Pubmed Id: 15601833, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 22411813, MOUSE PHENOTYPE ID: MGI:106653
HumanCDKN2B1030cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
img Jax MP, Pubmed Id: 11171393, MOUSE PHENOTYPE ID: MGI:2177412
img Jax MP, Pubmed Id: 15057277, MOUSE PHENOTYPE ID: MGI:3802582
img Jax MP, Pubmed Id: 19454665, MOUSE PHENOTYPE ID: MGI:105043
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 22411813, MOUSE PHENOTYPE ID: MGI:106653
img Jax MP, Pubmed Id: 15601833, MOUSE PHENOTYPE ID: MGI:2180021
HumanRUNX3864runt-related transcription factor 3
INFERRED
HumanAHR196aryl hydrocarbon receptor
img Jax MP, Pubmed Id: 15894281, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 22411813, MOUSE PHENOTYPE ID: MGI:106653
img Jax MP, Pubmed Id: 11171393, MOUSE PHENOTYPE ID: MGI:2177412
img Jax MP, Pubmed Id: 19454665, MOUSE PHENOTYPE ID: MGI:105043
img Jax MP, Pubmed Id: 15601833, MOUSE PHENOTYPE ID: MGI:2180021
img Jax MP, Pubmed Id: 15057277, MOUSE PHENOTYPE ID: MGI:3802582
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008117abnormal Langerhans cell morphology0self