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Details
Link-It Detail - Jax Mouse Phenotype - abnormal macrophage differentiation
Debug Stats
  • ### Total Build Time: 31 ms 36.854 KB
  • CONCEPT_NAME gt=17 ms Completed: 17 ms rowSize= 398 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 19.938 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.173 KB
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Jax Mouse Phenotype (1)
abnormal macrophage differentiation MP:0008113
Definition (1)
atypical production of or inability to produce the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells
Parents (2)
img abnormal mononuclear cell differentiation MP:0002445
img abnormal macrophage morphology MP:0002446
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal mononuclear cell differentiation MP:0002445
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal mononuclear cell differentiation MP:0002445
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img abnormal mononuclear cell differentiation MP:0002445
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053977img abnormal mononuclear cell differentiation MP:0002445
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal macrophage morphology MP:0002446
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanIKZF110320IKAROS family zinc finger 1 (Ikaros)
img Jax MP, Pubmed Id: 8896458, MOUSE PHENOTYPE ID: MGI:98282
img Jax MP, Pubmed Id: 15322156, MOUSE PHENOTYPE ID: MGI:1261423
img Jax MP, Pubmed Id: 16449662, MOUSE PHENOTYPE ID: MGI:97874
img Jax MP, Pubmed Id: 22624878, MOUSE PHENOTYPE ID: MGI:96897
img Jax MP, Pubmed Id: 12871645, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
HumanRB15925retinoblastoma 1
img Jax MP, Pubmed Id: 15322156, MOUSE PHENOTYPE ID: MGI:1261423
img Jax MP, Pubmed Id: 22624878, MOUSE PHENOTYPE ID: MGI:96897
img Jax MP, Pubmed Id: 12871645, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 16449662, MOUSE PHENOTYPE ID: MGI:97874
img Jax MP, Pubmed Id: 8896458, MOUSE PHENOTYPE ID: MGI:98282
HumanCSF1R1436colony stimulating factor 1 receptor
img Jax MP, Pubmed Id: 16449662, MOUSE PHENOTYPE ID: MGI:97874
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 22624878, MOUSE PHENOTYPE ID: MGI:96897
img Jax MP, Pubmed Id: 12871645, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 15322156, MOUSE PHENOTYPE ID: MGI:1261423
img Jax MP, Pubmed Id: 8896458, MOUSE PHENOTYPE ID: MGI:98282
HumanCASP8841caspase 8, apoptosis-related cysteine peptidase
img Jax MP, Pubmed Id: 16444257, MOUSE PHENOTYPE ID: MGI:1339758
img Jax MP, Pubmed Id: 22624878, MOUSE PHENOTYPE ID: MGI:96897
img Jax MP, Pubmed Id: 8896458, MOUSE PHENOTYPE ID: MGI:98282
img Jax MP, Pubmed Id: 12871645, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 16449662, MOUSE PHENOTYPE ID: MGI:97874
img Jax MP, Pubmed Id: 15322156, MOUSE PHENOTYPE ID: MGI:1261423
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008113abnormal macrophage differentiation0self