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Details
Link-It Detail - Jax Mouse Phenotype - abnormal CD4-positive T cell differentiation
Debug Stats
  • ### Total Build Time: 159 ms 34.539 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 416 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 354 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 194 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=26 ms Completed: 26 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 1.037 KB
  • CONCEPT_CHILDREN gt=9 ms Completed: 9 ms rowSize= 1.524 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 13.715 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=111 ms Completed: 111 ms rowSize= 15.995 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.182 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal CD4-positive T cell differentiation MP:0008076
Definition (1)
atypical production of or inability to produce the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production
Synonyms (1)
"abnormal CD4+ T cell differentiation" EXACT
Parents (2)
img abnormal CD4-positive T cell morphology MP:0002432
img abnormal T cell differentiation MP:0002145
Children (3)
img abnormal T-helper 2 cell differentiation MP:0008092
img abnormal T follicular helper cell differentiation MP:0010188
img abnormal T-helper 1 cell differentiation MP:0008088
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal CD4-positive T cell morphology MP:0002432
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal CD4-positive T cell morphology MP:0002432
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal CD4-positive T cell morphology MP:0002432
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal T cell differentiation MP:0002145
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal T cell differentiation MP:0002145
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal T cell differentiation MP:0002145
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal T cell differentiation MP:0002145
img mammalian phenotype MP:0000001img cellular phenotype MP:00053848img abnormal T cell differentiation MP:0002145
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal T cell differentiation MP:0002145
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal T cell differentiation MP:0002145
Genes (59)

Species:
human : 59
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanIL27246778interleukin 27
Click here to display 45 evidence detail records.
HumanIL23R149233interleukin 23 receptor
Click here to display 45 evidence detail records.
HumanCLEC6A93978C-type lectin domain family 6, member A
Click here to display 45 evidence detail records.
HumanRSAD291543radical S-adenosyl methionine domain containing 2
INFERRED
HumanTSLP85480thymic stromal lymphopoietin
INFERRED
HumanCARD1184433caspase recruitment domain family, member 11
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanBHLHE4179365basic helix-loop-helix family, member e41
INFERRED
HumanSEMA4A64218sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
INFERRED
HumanLIME154923Lck interacting transmembrane adaptor 1
Click here to display 45 evidence detail records.
HumanSASH354440SAM and SH3 domain containing 3
Click here to display 45 evidence detail records.
HumanFOXP350943forkhead box P3
Click here to display 45 evidence detail records.
HumanIL21R50615interleukin 21 receptor
Click here to display 45 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 45 evidence detail records.
HumanCD27429126CD274 molecule
INFERRED
HumanSIT127240signaling threshold regulating transmembrane adaptor 1
INFERRED
HumanIL17RA23765interleukin 17 receptor A
INFERRED
HumanICOSLG23308inducible T-cell co-stimulator ligand
INFERRED
HumanRFTN123180raftlin, lipid raft linker 1
Click here to display 45 evidence detail records.
HumanGADD45G10912growth arrest and DNA-damage-inducible, gamma
INFERRED
HumanBATF10538basic leucine zipper transcription factor, ATF-like
Click here to display 45 evidence detail records.
HumanTOX9760thymocyte selection-associated high mobility group box
Click here to display 45 evidence detail records.
HumanCD839308CD83 molecule
Click here to display 45 evidence detail records.
HumanKSR18844kinase suppressor of ras 1
Click here to display 45 evidence detail records.
HumanSOCS18651suppressor of cytokine signaling 1
Click here to display 45 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008076abnormal CD4-positive T cell differentiation0self