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Details
Link-It Detail - Jax Mouse Phenotype - absent NK cells
Debug Stats
  • ### Total Build Time: 91 ms 60.893 KB
  • CONCEPT_NAME gt=10 ms Completed: 10 ms rowSize= 358 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 400 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 185 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 1.009 KB
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 580 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=33 ms Completed: 33 ms rowSize= 13.604 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=25 ms Completed: 25 ms rowSize= 43.494 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
absent NK cells MP:0008046
Definition (1)
absence of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Synonyms (1)
"absent natural killer cells" EXACT
Parents (2)
img absent lymphocyte MP:0000726
img decreased NK cell number MP:0008045
Children (1)
img absent uterine NK cells MP:0008047
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img absent lymphocyte MP:0000726
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased NK cell number MP:0008045
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img decreased NK cell number MP:0008045
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img decreased NK cell number MP:0008045
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img decreased NK cell number MP:0008045
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img decreased NK cell number MP:0008045
Genes (7)

Species:
human : 7
SpeciesGeneGeneIdGene NameEvidence
HumanIKZF110320IKAROS family zinc finger 1 (Ikaros)
img Jax MP, Pubmed Id: 7937778, MOUSE PHENOTYPE ID: MGI:3052630
img Jax MP, Pubmed Id: 17082625, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 9169772, MOUSE PHENOTYPE ID: MGI:96559
img Jax MP, Pubmed Id: 12586624, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8986714, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 8777722, MOUSE PHENOTYPE ID: MGI:99928
img Jax MP, Pubmed Id: 8562967, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 17086188, MOUSE PHENOTYPE ID: MGI:96397
img Jax MP, Pubmed Id: 7697543, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
HumanJAK33718Janus kinase 3
img Jax MP, Pubmed Id: 17082625, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8562967, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 17086188, MOUSE PHENOTYPE ID: MGI:96397
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8986714, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 9169772, MOUSE PHENOTYPE ID: MGI:96559
img Jax MP, Pubmed Id: 7937778, MOUSE PHENOTYPE ID: MGI:3052630
img Jax MP, Pubmed Id: 12586624, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8777722, MOUSE PHENOTYPE ID: MGI:99928
img Jax MP, Pubmed Id: 7697543, MOUSE PHENOTYPE ID: MGI:96551
HumanIL153600interleukin 15
INFERRED
HumanIL63569interleukin 6 (interferon, beta 2)
img Jax MP, Pubmed Id: 17086188, MOUSE PHENOTYPE ID: MGI:96397
img Jax MP, Pubmed Id: 17082625, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8562967, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8986714, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 8777722, MOUSE PHENOTYPE ID: MGI:99928
img Jax MP, Pubmed Id: 7937778, MOUSE PHENOTYPE ID: MGI:3052630
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 12586624, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 9169772, MOUSE PHENOTYPE ID: MGI:96559
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 7697543, MOUSE PHENOTYPE ID: MGI:96551
HumanIL2RG3561interleukin 2 receptor, gamma
img Jax MP, Pubmed Id: 7937778, MOUSE PHENOTYPE ID: MGI:3052630
img Jax MP, Pubmed Id: 17082625, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 12586624, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8777722, MOUSE PHENOTYPE ID: MGI:99928
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8986714, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 8562967, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 9169772, MOUSE PHENOTYPE ID: MGI:96559
img Jax MP, Pubmed Id: 17086188, MOUSE PHENOTYPE ID: MGI:96397
img Jax MP, Pubmed Id: 7697543, MOUSE PHENOTYPE ID: MGI:96551
HumanIL2RB3560interleukin 2 receptor, beta
INFERRED
HumanID23398inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
img Jax MP, Pubmed Id: 8986714, MOUSE PHENOTYPE ID: MGI:1342540
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 7937778, MOUSE PHENOTYPE ID: MGI:3052630
img Jax MP, Pubmed Id: 9169772, MOUSE PHENOTYPE ID: MGI:96559
img Jax MP, Pubmed Id: 17086188, MOUSE PHENOTYPE ID: MGI:96397
img Jax MP, Pubmed Id: 8777722, MOUSE PHENOTYPE ID: MGI:99928
img Jax MP, Pubmed Id: 7831294, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 8562967, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 17082625, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 12586624, MOUSE PHENOTYPE ID: MGI:96551
img Jax MP, Pubmed Id: 7697543, MOUSE PHENOTYPE ID: MGI:96551
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008046absent NK cells0self