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Details
Link-It Detail - Jax Mouse Phenotype - increased susceptibility to type III hypersensitivity reaction
Debug Stats
  • ### Total Build Time: 35 ms 23.315 KB
  • CONCEPT_NAME gt=14 ms Completed: 14 ms rowSize= 452 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 475 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 226 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.038 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=8 ms Completed: 8 ms rowSize= 4.281 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 15.519 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.199 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased susceptibility to type III hypersensitivity reaction MP:0005615
Definition (1)
greater likelihood of developing tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via antibodies encountering circulating antigen; Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury
Synonyms (1)
"increased susceptibility to immune complex mediated hypersensitivity" EXACT
Parents (2)
img abnormal type III hypersensitivity reaction MP:0002533
img increased acute inflammation MP:0005088
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal type III hypersensitivity reaction MP:0002533
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal type III hypersensitivity reaction MP:0002533
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img increased acute inflammation MP:0005088
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanCFH3075complement factor H
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:3529863
img Jax MP, Pubmed Id: 8793508, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:1278323
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:2681652
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87958
img Jax MP, Pubmed Id: 12091909, MOUSE PHENOTYPE ID: MGI:88385
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87959
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:1278323
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87958
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87959
HumanFAS355Fas cell surface death receptor
img Jax MP, Pubmed Id: 8793508, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87959
img Jax MP, Pubmed Id: 12091909, MOUSE PHENOTYPE ID: MGI:88385
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:3529863
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:2681652
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:1278323
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87958
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87959
img Jax MP, Pubmed Id: 15634937, MOUSE PHENOTYPE ID: MGI:1278323
img Jax MP, Pubmed Id: 6217253, MOUSE PHENOTYPE ID: MGI:87958
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005615increased susceptibility to type III hypersensitivity reaction0self