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Details
Link-It Detail - Jax Mouse Phenotype - decreased susceptibility to type II hypersensitivity reaction
Debug Stats
  • ### Total Build Time: 36 ms 11.961 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 450 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 418 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 217 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 1.037 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=18 ms Completed: 18 ms rowSize= 4.279 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 4.234 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.198 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased susceptibility to type II hypersensitivity reaction MP:0005612
Definition (1)
less likelihood of or resistance to developing a response caused by an Ag-Ab reaction; antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues; most often involves IgG and IgM; complement activation is usually involved
Synonyms (1)
"increased resistance to antibody-mediated cellular toxicity" EXACT
Parents (2)
img decreased acute inflammation MP:0005087
img abnormal type II hypersensitivity reaction MP:0002532
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img decreased acute inflammation MP:0005087
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal type II hypersensitivity reaction MP:0002532
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal type II hypersensitivity reaction MP:0002532
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanFCGR2A2212Fc fragment of IgG, low affinity IIa, receptor (CD32)
img Jax MP, Pubmed Id: 10760808, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 8769481, MOUSE PHENOTYPE ID: MGI:95500
HumanCD40958CD40 molecule, TNF receptor superfamily member 5
img Jax MP, Pubmed Id: 10760808, MOUSE PHENOTYPE ID: MGI:88336
img Jax MP, Pubmed Id: 8769481, MOUSE PHENOTYPE ID: MGI:95500
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005612decreased susceptibility to type II hypersensitivity reaction0self