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Details
Link-It Detail - Jax Mouse Phenotype - increased susceptibility to type I hypersensitivity reaction
Debug Stats
  • ### Total Build Time: 51 ms 21.694 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 448 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 439 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 193 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.036 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 4.277 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=34 ms Completed: 34 ms rowSize= 13.977 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.197 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased susceptibility to type I hypersensitivity reaction MP:0005596
Definition (1)
greater likelihood of developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Synonyms (1)
"decreased resistance to anaphylaxis" EXACT
Parents (2)
img increased acute inflammation MP:0005088
img abnormal type I hypersensitivity reaction MP:0002531
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img increased acute inflammation MP:0005088
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal type I hypersensitivity reaction MP:0002531
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal type I hypersensitivity reaction MP:0002531
Genes (23)

Species:
human : 23
SpeciesGeneGeneIdGene NameEvidence
HumanCD300LF146722CD300 molecule-like family member f
Click here to display 37 evidence detail records.
HumanIL2564806interleukin 25
Click here to display 37 evidence detail records.
HumanTRPM454795transient receptor potential cation channel, subfamily M, member 4
Click here to display 37 evidence detail records.
HumanDUSP1011221dual specificity phosphatase 10
Click here to display 37 evidence detail records.
HumanCORO1A11151coronin, actin binding protein, 1A
Click here to display 37 evidence detail records.
HumanLPAR29170lysophosphatidic acid receptor 2
Click here to display 37 evidence detail records.
HumanPIP5K1B8395phosphatidylinositol-4-phosphate 5-kinase, type I, beta
Click here to display 37 evidence detail records.
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
Click here to display 37 evidence detail records.
HumanRGS136003regulator of G-protein signaling 13
Click here to display 37 evidence detail records.
HumanPTAFR5724platelet-activating factor receptor
Click here to display 37 evidence detail records.
HumanPPIA5478peptidylprolyl isomerase A (cyclophilin A)
Click here to display 37 evidence detail records.
HumanPLA2G4A5321phospholipase A2, group IVA (cytosolic, calcium-dependent)
Click here to display 37 evidence detail records.
HumanMME4311membrane metallo-endopeptidase
Click here to display 37 evidence detail records.
HumanIL133596interleukin 13
Click here to display 37 evidence detail records.
HumanIL4R3566interleukin 4 receptor
Click here to display 37 evidence detail records.
HumanFYN2534FYN oncogene related to SRC, FGR, YES
Click here to display 37 evidence detail records.
HumanFCGR2B2213Fc fragment of IgG, low affinity IIb, receptor (CD32)
Click here to display 37 evidence detail records.
HumanFCER22208Fc fragment of IgE, low affinity II, receptor for (CD23)
Click here to display 37 evidence detail records.
HumanFCER1A2205Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Click here to display 37 evidence detail records.
HumanDUSP11843dual specificity phosphatase 1
Click here to display 37 evidence detail records.
HumanCD28940CD28 molecule
Click here to display 37 evidence detail records.
HumanC3AR1719complement component 3a receptor 1
Click here to display 37 evidence detail records.
HumanADORA2B136adenosine A2b receptor
Click here to display 37 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005596increased susceptibility to type I hypersensitivity reaction0self