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Details
Link-It Detail - Jax Mouse Phenotype - abnormal renin activity
Debug Stats
  • ### Total Build Time: 34 ms 28.312 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 374 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 236 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 195 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 588 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.018 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.587 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=18 ms Completed: 18 ms rowSize= 23.042 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal renin activity MP:0005581
Definition (1)
altered ability of this enzyme to cleave angiotensionogen and create angiotensin I
Synonyms (1)
"abnormal angiotensionogenase activity" EXACT
Parents (1)
img abnormal enzyme/coenzyme activity MP:0005584
Children (2)
img increased renin activity MP:0005582
img decreased renin activity MP:0005583
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img abnormal enzyme/coenzyme activity MP:0005584
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanCRIM151232cysteine rich transmembrane BMP regulator 1 (chordin-like)
img Jax MP, Pubmed Id: 19776720, MOUSE PHENOTYPE ID: MGI:1354756
img Jax MP, Pubmed Id: 17275289, MOUSE PHENOTYPE ID: MGI:103076
img Jax MP, Pubmed Id: 9458926, MOUSE PHENOTYPE ID: MGI:97367
img Jax MP, Pubmed Id: 10359563, MOUSE PHENOTYPE ID: MGI:97794
img Jax MP, Pubmed Id: 16822937, MOUSE PHENOTYPE ID: MGI:95777
HumanVAV310451vav 3 guanine nucleotide exchange factor
INFERRED
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img Jax MP, Pubmed Id: 17275289, MOUSE PHENOTYPE ID: MGI:103076
img Jax MP, Pubmed Id: 19776720, MOUSE PHENOTYPE ID: MGI:1354756
img Jax MP, Pubmed Id: 16822937, MOUSE PHENOTYPE ID: MGI:95777
img Jax MP, Pubmed Id: 10359563, MOUSE PHENOTYPE ID: MGI:97794
img Jax MP, Pubmed Id: 9458926, MOUSE PHENOTYPE ID: MGI:97367
HumanVAV27410vav 2 guanine nucleotide exchange factor
INFERRED
HumanSLC12A16557solute carrier family 12 (sodium/potassium/chloride transporter), member 1
INFERRED
HumanSLC5A26524solute carrier family 5 (sodium/glucose cotransporter), member 2
INFERRED
HumanPTGER25732prostaglandin E receptor 2 (subtype EP2), 53kDa
img Jax MP, Pubmed Id: 10359563, MOUSE PHENOTYPE ID: MGI:97794
img Jax MP, Pubmed Id: 17275289, MOUSE PHENOTYPE ID: MGI:103076
img Jax MP, Pubmed Id: 16822937, MOUSE PHENOTYPE ID: MGI:95777
img Jax MP, Pubmed Id: 19776720, MOUSE PHENOTYPE ID: MGI:1354756
img Jax MP, Pubmed Id: 9458926, MOUSE PHENOTYPE ID: MGI:97367
HumanPTGER15731prostaglandin E receptor 1 (subtype EP1), 42kDa
INFERRED
HumanNPPA4878natriuretic peptide A
img Jax MP, Pubmed Id: 19776720, MOUSE PHENOTYPE ID: MGI:1354756
img Jax MP, Pubmed Id: 17275289, MOUSE PHENOTYPE ID: MGI:103076
img Jax MP, Pubmed Id: 10359563, MOUSE PHENOTYPE ID: MGI:97794
img Jax MP, Pubmed Id: 9458926, MOUSE PHENOTYPE ID: MGI:97367
img Jax MP, Pubmed Id: 16822937, MOUSE PHENOTYPE ID: MGI:95777
HumanNOS24843nitric oxide synthase 2, inducible
INFERRED
HumanNR3C24306nuclear receptor subfamily 3, group C, member 2
INFERRED
HumanNR3C12908nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
INFERRED
HumanEDNRB1910endothelin receptor type B
INFERRED
HumanDRD31814dopamine receptor D3
INFERRED
HumanACE1636angiotensin I converting enzyme
INFERRED
HumanCYP11B11584cytochrome P450, family 11, subfamily B, polypeptide 1
INFERRED
HumanAGTR1185angiotensin II receptor, type 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005581abnormal renin activity0self