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Details
Link-It Detail - Jax Mouse Phenotype - increased susceptibility to autoimmune disorder
Debug Stats
  • ### Total Build Time: 265 ms 23.681 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 422 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 351 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 201 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 600 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 3.992 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.590 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=55 ms Completed: 55 ms rowSize= 15.232 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.185 KB
  • CONCEPT_ANCILLARY gt=201 ms Completed: 201 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased susceptibility to autoimmune disorder MP:0005350
Definition (1)
greater likelihood that an organism will develop disease characterized by production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides
Synonyms (1)
"decreased resistance to autoimmune disorder" EXACT
Parents (1)
img altered susceptibility to autoimmune disorder MP:0002425
Children (8)
img increased susceptibility to autoimmune diabetes MP:0004803
img increased susceptibility to experimental autoimmune myasthenia gravis MP:0004823
img increased susceptibility to experimental autoimmune uveoretinitis MP:0004821
img increased susceptibility to autoimmune hemolytic anemia MP:0004827
img increased susceptibility to experimental autoimmune encephalomyelitis MP:0004799
img increased susceptibility to experimental autoimmune thyroiditis MP:0004825
img increased susceptibility to systemic lupus erythematosus MP:0004801
img increased susceptibility to induced arthritis MP:0003724
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img altered susceptibility to autoimmune disorder MP:0002425
Genes (128)

Species:
human : 128
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanIL27246778interleukin 27
INFERRED
HumanTIGIT201633T cell immunoreceptor with Ig and ITIM domains
INFERRED
HumanBTLA151888B and T lymphocyte associated
INFERRED
HumanCD300LF146722CD300 molecule-like family member f
INFERRED
HumanCD27680381CD276 molecule
INFERRED
HumanPDCD1LG280380programmed cell death 1 ligand 2
INFERRED
HumanVTCN179679V-set domain containing T cell activation inhibitor 1
INFERRED
HumanRNF12879589ring finger protein 128, E3 ubiquitin protein ligase
INFERRED
HumanIL2564806interleukin 25
INFERRED
HumanIL2159067interleukin 21
INFERRED
HumanENTPD757089ectonucleoside triphosphate diphosphohydrolase 7
INFERRED
HumanHR55806hair growth associated
Click here to display 66 evidence detail records.
HumanCYTL154360cytokine-like 1
INFERRED
HumanTLR954106toll-like receptor 9
INFERRED
HumanACKR451554atypical chemokine receptor 4
INFERRED
HumanTLR751284toll-like receptor 7
INFERRED
HumanFOXP350943forkhead box P3
Click here to display 66 evidence detail records.
HumanIL21R50615interleukin 21 receptor
INFERRED
HumanICOS29851inducible T-cell co-stimulator
INFERRED
HumanUSP2529761ubiquitin specific peptidase 25
INFERRED
HumanCD27429126CD274 molecule
Click here to display 66 evidence detail records.
HumanSIT127240signaling threshold regulating transmembrane adaptor 1
INFERRED
HumanLAT27040linker for activation of T cells
INFERRED
HumanHAVCR126762hepatitis A virus cellular receptor 1
INFERRED
HumanTUSC211334tumor suppressor candidate 2
Click here to display 66 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005350increased susceptibility to autoimmune disorder0self