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Details
Link-It Detail - Jax Mouse Phenotype - increased thyroid-stimulating hormone level
Debug Stats
  • ### Total Build Time: 22 ms 36.721 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 244 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 177 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.042 KB
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 612 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 2.948 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 29.992 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased thyroid-stimulating hormone level MP:0005135
Definition (1)
greater amount of the hormone that stimulates the growth and function of the thyroid gland
Synonyms (1)
"increased TSH level" EXACT
Parents (2)
img increased pituitary hormone level MP:0003973
img abnormal thyroid-stimulating hormone level MP:0003971
Children (1)
img increased circulating thyroid-stimulating hormone level MP:0005122
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img increased pituitary hormone level MP:0003973
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal thyroid-stimulating hormone level MP:0003971
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanDUOX250506dual oxidase 2
INFERRED
HumanNCOA18648nuclear receptor coactivator 1
INFERRED
HumanPAX87849paired box 8
INFERRED
HumanTSHR7253thyroid stimulating hormone receptor
INFERRED
HumanTRH7200thyrotropin-releasing hormone
img Jax MP, Pubmed Id: 8670802, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 9380725, MOUSE PHENOTYPE ID: MGI:98823
img Jax MP, Pubmed Id: 20375239, MOUSE PHENOTYPE ID: MGI:99829
img Jax MP, Pubmed Id: 16709608, MOUSE PHENOTYPE ID: MGI:1203732
img Jax MP, Pubmed Id: 11496110, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 17210747, MOUSE PHENOTYPE ID: MGI:98742
HumanTPO7173thyroid peroxidase
INFERRED
HumanNKX2-17080
INFERRED
HumanTHRB7068thyroid hormone receptor, beta
img Jax MP, Pubmed Id: 11496110, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 20375239, MOUSE PHENOTYPE ID: MGI:99829
img Jax MP, Pubmed Id: 9380725, MOUSE PHENOTYPE ID: MGI:98823
img Jax MP, Pubmed Id: 16709608, MOUSE PHENOTYPE ID: MGI:1203732
img Jax MP, Pubmed Id: 17210747, MOUSE PHENOTYPE ID: MGI:98742
img Jax MP, Pubmed Id: 8670802, MOUSE PHENOTYPE ID: MGI:98743
HumanTHRA7067thyroid hormone receptor, alpha
img Jax MP, Pubmed Id: 16709608, MOUSE PHENOTYPE ID: MGI:1203732
img Jax MP, Pubmed Id: 11496110, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 9380725, MOUSE PHENOTYPE ID: MGI:98823
img Jax MP, Pubmed Id: 8670802, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 20375239, MOUSE PHENOTYPE ID: MGI:99829
img Jax MP, Pubmed Id: 17210747, MOUSE PHENOTYPE ID: MGI:98742
HumanTG7038thyroglobulin
INFERRED
HumanSLC16A26567solute carrier family 16, member 2 (thyroid hormone transporter)
img Jax MP, Pubmed Id: 11496110, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 20375239, MOUSE PHENOTYPE ID: MGI:99829
img Jax MP, Pubmed Id: 17210747, MOUSE PHENOTYPE ID: MGI:98742
img Jax MP, Pubmed Id: 9380725, MOUSE PHENOTYPE ID: MGI:98823
img Jax MP, Pubmed Id: 8670802, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 16709608, MOUSE PHENOTYPE ID: MGI:1203732
HumanPITX25308paired-like homeodomain 2
INFERRED
HumanHOXA53202homeobox A5
INFERRED
HumanFOXE12304forkhead box E1 (thyroid transcription factor 2)
INFERRED
HumanDIO31735deiodinase, iodothyronine, type III
INFERRED
HumanDIO21734deiodinase, iodothyronine, type II
INFERRED
HumanRUNX2860runt-related transcription factor 2
img Jax MP, Pubmed Id: 17210747, MOUSE PHENOTYPE ID: MGI:98742
img Jax MP, Pubmed Id: 16709608, MOUSE PHENOTYPE ID: MGI:1203732
img Jax MP, Pubmed Id: 9380725, MOUSE PHENOTYPE ID: MGI:98823
img Jax MP, Pubmed Id: 11496110, MOUSE PHENOTYPE ID: MGI:98743
img Jax MP, Pubmed Id: 20375239, MOUSE PHENOTYPE ID: MGI:99829
img Jax MP, Pubmed Id: 8670802, MOUSE PHENOTYPE ID: MGI:98743
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005135increased thyroid-stimulating hormone level0self