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Details
Link-It Detail - Jax Mouse Phenotype - abnormal B-1 B cell morphology
Debug Stats
  • ### Total Build Time: 24 ms 24.715 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 388 bytes
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  • CONCEPT_GENES gt=17 ms Completed: 17 ms rowSize= 14.562 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.168 KB
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Jax Mouse Phenotype (1)
abnormal B-1 B cell morphology MP:0004940
Definition (1)
any structural anomaly of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and are enriched for self-reactivity; B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas
Synonyms (1)
"abnormal B-1 B lymphocyte morphology" EXACT
Parents (1)
img abnormal mature B cell morphology MP:0008171
Children (3)
img abnormal B-1b B cell morphology MP:0008165
img abnormal B-1 B cell number MP:0004976
img abnormal B-1a B cell morphology MP:0008164
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal mature B cell morphology MP:0008171
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal mature B cell morphology MP:0008171
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal mature B cell morphology MP:0008171
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal mature B cell morphology MP:0008171
Genes (82)

Species:
human : 82
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
INFERRED
HumanIGLL5100423062immunoglobulin lambda-like polypeptide 5
INFERRED
HumanATP11C286410ATPase, class VI, type 11C
INFERRED
HumanTAB3257397TGF-beta activated kinase 1/MAP3K7 binding protein 3
INFERRED
HumanGIMAP1170575GTPase, IMAP family member 1
INFERRED
HumanSPNS2124976spinster homolog 2 (Drosophila)
INFERRED
HumanPIK3AP1118788phosphoinositide-3-kinase adaptor protein 1
INFERRED
HumanFNIP196459folliculin interacting protein 1
INFERRED
HumanSIGLEC1089790sialic acid binding Ig-like lectin 10
INFERRED
HumanSPPL2A84888signal peptide peptidase like 2A
INFERRED
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
INFERRED
HumanCARD1184433caspase recruitment domain family, member 11
INFERRED
HumanDOCK881704dedicator of cytokinesis 8
INFERRED
HumanSAMSN164092SAM domain, SH3 domain and nuclear localization signals 1
INFERRED
HumanBANK155024B-cell scaffold protein with ankyrin repeats 1
INFERRED
HumanPPP2R3C55012protein phosphatase 2, regulatory subunit B'', gamma
INFERRED
HumanSIAE54414sialic acid acetylesterase
INFERRED
HumanTLR954106toll-like receptor 9
INFERRED
HumanTLR851311toll-like receptor 8
INFERRED
HumanBLNK29760B-cell linker
INFERRED
HumanDLL128514delta-like 1 (Drosophila)
INFERRED
HumanDAPP127071dual adaptor of phosphotyrosine and 3-phosphoinositides
INFERRED
HumanPLCL223228phospholipase C-like 2
INFERRED
HumanLILRB311025leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
INFERRED
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004940abnormal B-1 B cell morphology0self