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Details
Link-It Detail - Jax Mouse Phenotype - increased susceptibility to experimental autoimmune uveoretinitis
Debug Stats
  • ### Total Build Time: 10 ms 18.406 KB
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  • Reload Stats
Jax Mouse Phenotype (1)
increased susceptibility to experimental autoimmune uveoretinitis MP:0004821
Definition (1)
greater likelihood that an organism will develop disease symptoms similar to human sight-threatening inflammatory eye diseases upon induction by peripheral immunization with one of several uveitogenic retinal proteins (or with peptides derived from them), or by the adoptive transfer of lymphocytes specific to these antigens
Synonyms (1)
"decreased resistance to experimental autoimmune uveitis" EXACT
Parents (1)
img increased susceptibility to autoimmune disorder MP:0005350
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img increased susceptibility to autoimmune disorder MP:0005350
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanNFE2L24780nuclear factor, erythroid 2-like 2
img Jax MP, Pubmed Id: 19410644, MOUSE PHENOTYPE ID: MGI:108420
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:107655
img Jax MP, Pubmed Id: 12414514, MOUSE PHENOTYPE ID: MGI:1196990
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:95602
HumanCD2004345CD200 molecule
img Jax MP, Pubmed Id: 12414514, MOUSE PHENOTYPE ID: MGI:1196990
img Jax MP, Pubmed Id: 19410644, MOUSE PHENOTYPE ID: MGI:108420
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:95602
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:107655
HumanIFNGR13459interferon gamma receptor 1
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:95602
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:107655
img Jax MP, Pubmed Id: 12414514, MOUSE PHENOTYPE ID: MGI:1196990
img Jax MP, Pubmed Id: 19410644, MOUSE PHENOTYPE ID: MGI:108420
HumanFYN2534FYN oncogene related to SRC, FGR, YES
img Jax MP, Pubmed Id: 12414514, MOUSE PHENOTYPE ID: MGI:1196990
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:95602
img Jax MP, Pubmed Id: 19410644, MOUSE PHENOTYPE ID: MGI:108420
img Jax MP, Pubmed Id: 15902435, MOUSE PHENOTYPE ID: MGI:107655
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004821increased susceptibility to experimental autoimmune uveoretinitis0self