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Details
Link-It Detail - Jax Mouse Phenotype - increased susceptibility to autoimmune diabetes
Debug Stats
  • ### Total Build Time: 101 ms 17.681 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 422 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 338 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 201 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 602 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=7 ms Completed: 7 ms rowSize= 1.592 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=84 ms Completed: 84 ms rowSize= 13.226 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.185 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased susceptibility to autoimmune diabetes MP:0004803
Definition (1)
greater likelihood that an organism will develop inflammatory pancreatic disease resulting from the body attacking and destroying the insulin-producing beta islet cells of the pancreas
Synonyms (1)
"decreased resistance to autoimmune diabetes" EXACT
Parents (1)
img increased susceptibility to autoimmune disorder MP:0005350
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img increased susceptibility to autoimmune disorder MP:0005350
Genes (22)

Species:
human : 22
SpeciesGeneGeneIdGene NameEvidence
HumanPDCD1LG280380programmed cell death 1 ligand 2
Click here to display 87 evidence detail records.
HumanVTCN179679V-set domain containing T cell activation inhibitor 1
Click here to display 87 evidence detail records.
HumanCD27429126CD274 molecule
Click here to display 87 evidence detail records.
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
Click here to display 87 evidence detail records.
HumanIRS28660insulin receptor substrate 2
Click here to display 87 evidence detail records.
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
Click here to display 87 evidence detail records.
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
Click here to display 87 evidence detail records.
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
Click here to display 87 evidence detail records.
HumanTLR57100toll-like receptor 5
Click here to display 87 evidence detail records.
HumanSTAT66778signal transducer and activator of transcription 6, interleukin-4 induced
Click here to display 87 evidence detail records.
HumanPTPRN5798protein tyrosine phosphatase, receptor type, N
Click here to display 87 evidence detail records.
HumanPRKDC5591protein kinase, DNA-activated, catalytic polypeptide
Click here to display 87 evidence detail records.
HumanPDCD15133programmed cell death 1
Click here to display 87 evidence detail records.
HumanLEPR3953leptin receptor
Click here to display 87 evidence detail records.
HumanINS3630insulin
Click here to display 87 evidence detail records.
HumanIL23558interleukin 2
Click here to display 87 evidence detail records.
HumanHLA-DQB13119
Click here to display 87 evidence detail records.
HumanE2F11869E2F transcription factor 1
Click here to display 87 evidence detail records.
HumanCDK21017cyclin-dependent kinase 2
Click here to display 87 evidence detail records.
HumanCD38952CD38 molecule
Click here to display 87 evidence detail records.
HumanCD86942CD86 molecule
Click here to display 87 evidence detail records.
HumanCD28940CD28 molecule
Click here to display 87 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004803increased susceptibility to autoimmune diabetes0self