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Details
Link-It Detail - Jax Mouse Phenotype - impaired acrosome reaction
Debug Stats
  • ### Total Build Time: 104 ms 20.121 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 380 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 259 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.017 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 2.917 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=84 ms Completed: 84 ms rowSize= 14.247 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.164 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
impaired acrosome reaction MP:0004542
Definition (1)
abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs
Parents (2)
img abnormal fertilization MP:0005410
img impaired sperm capacitation MP:0003666
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img reproductive system phenotype MP:00053895img abnormal fertilization MP:0005410
img mammalian phenotype MP:0000001img reproductive system phenotype MP:00053897img impaired sperm capacitation MP:0003666
Genes (23)

Species:
human : 23
SpeciesGeneGeneIdGene NameEvidence
HumanKCNU1157855potassium channel, subfamily U, member 1
Click here to display 35 evidence detail records.
HumanATP8B3148229ATPase, aminophospholipid transporter, class I, type 8B, member 3
Click here to display 35 evidence detail records.
HumanCATSPER2117155cation channel, sperm associated 2
Click here to display 35 evidence detail records.
HumanCATSPER1117144cation channel, sperm associated 1
Click here to display 35 evidence detail records.
HumanSLC26A8116369solute carrier family 26 (anion exchanger), member 8
Click here to display 35 evidence detail records.
HumanOAZ351686ornithine decarboxylase antizyme 3
Click here to display 35 evidence detail records.
HumanPRND23627prion protein 2 (dublet)
Click here to display 35 evidence detail records.
HumanPRSS2110942protease, serine, 21 (testisin)
Click here to display 35 evidence detail records.
HumanTNP27142transition protein 2 (during histone to protamine replacement)
Click here to display 35 evidence detail records.
HumanTALDO16888transaldolase 1
Click here to display 35 evidence detail records.
HumanPVRL25819poliovirus receptor-related 2 (herpesvirus entry mediator B)
Click here to display 35 evidence detail records.
HumanPRNP5621prion protein
Click here to display 35 evidence detail records.
HumanODF14956outer dense fiber of sperm tails 1
Click here to display 35 evidence detail records.
HumanNPC14864Niemann-Pick disease, type C1
Click here to display 35 evidence detail records.
HumanMFGE84240milk fat globule-EGF factor 8 protein
Click here to display 35 evidence detail records.
HumanSMCP4184sperm mitochondria-associated cysteine-rich protein
Click here to display 35 evidence detail records.
HumanHIST1H1A3024histone cluster 1, H1a
Click here to display 35 evidence detail records.
HumanGLRB2743glycine receptor, beta
Click here to display 35 evidence detail records.
HumanGLRA12741glycine receptor, alpha 1
Click here to display 35 evidence detail records.
HumanB4GALT12683UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Click here to display 35 evidence detail records.
HumanAPOB338apolipoprotein B
Click here to display 35 evidence detail records.
HumanCRISP1167cysteine-rich secretory protein 1
Click here to display 35 evidence detail records.
HumanADCY3109adenylate cyclase 3
Click here to display 35 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004542impaired acrosome reaction0self