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Details
Link-It Detail - Jax Mouse Phenotype - increased cellular sensitivity to ionizing radiation
Debug Stats
  • ### Total Build Time: 108 ms 21.048 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 432 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 228 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 209 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=1 ms Completed: 1 ms rowSize= 598 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 1.070 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.583 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=94 ms Completed: 94 ms rowSize= 15.628 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.189 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased cellular sensitivity to ionizing radiation MP:0004227
Definition (1)
increased incidence of cell death following exposure to ionizing radiation
Synonyms (1)
"decreased cellular resistance to ionizing radiation" EXACT
Parents (1)
img increased sensitivity to induced cell death MP:0008943
Children (2)
img increased cellular sensitivity to gamma-irradiation MP:0002007
img increased cellular sensitivity to X-ray irradiation MP:0002879
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img increased sensitivity to induced cell death MP:0008943
Genes (67)

Species:
human : 67
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMCM9254394minichromosome maintenance complex component 9
INFERRED
HumanRAD9B144715RAD9 homolog B (S. pombe)
INFERRED
HumanMCM884515minichromosome maintenance complex component 8
INFERRED
HumanMXD383463MAX dimerization protein 3
INFERRED
HumanNHEJ179840nonhomologous end-joining factor 1
INFERRED
HumanMCPH179648microcephalin 1
INFERRED
HumanDCLRE1C64421DNA cross-link repair 1C
Click here to display 43 evidence detail records.
HumanRIF155183RAP1 interacting factor homolog (yeast)
Click here to display 43 evidence detail records.
HumanUIMC151720ubiquitin interaction motif containing 1
INFERRED
HumanSIRT651548sirtuin 6
Click here to display 43 evidence detail records.
HumanAPEX227301APEX nuclease (apurinic/apyrimidinic endonuclease) 2
INFERRED
HumanRAD54B25788RAD54 homolog B (S. cerevisiae)
INFERRED
HumanSIRT123411sirtuin 1
Click here to display 43 evidence detail records.
HumanSWAP7023075SWAP switching B-cell complex 70kDa subunit
INFERRED
HumanPAXIP122976PAX interacting (with transcription-activation domain) protein 1
Click here to display 43 evidence detail records.
HumanCOPS610980COP9 signalosome subunit 6
INFERRED
HumanRAD5010111RAD50 homolog (S. cerevisiae)
Click here to display 43 evidence detail records.
HumanPARP210038poly (ADP-ribose) polymerase 2
INFERRED
HumanMDC19656mediator of DNA-damage checkpoint 1
Click here to display 43 evidence detail records.
HumanRNF79616ring finger protein 7
Click here to display 43 evidence detail records.
HumanMTA19112metastasis associated 1
Click here to display 43 evidence detail records.
HumanCRADD8738CASP2 and RIPK1 domain containing adaptor with death domain
INFERRED
HumanRAD54L8438RAD54-like (S. cerevisiae)
INFERRED
HumanSMC1A8243structural maintenance of chromosomes 1A
Click here to display 43 evidence detail records.
HumanXRCC57520X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Click here to display 43 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004227increased cellular sensitivity to ionizing radiation0self