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Details
Link-It Detail - Jax Mouse Phenotype - decreased hepatocyte proliferation
Debug Stats
  • ### Total Build Time: 34 ms 23.398 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 236 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 190 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.025 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.916 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=28 ms Completed: 28 ms rowSize= 17.330 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased hepatocyte proliferation MP:0004001
Definition (1)
reduction in the expansion rate of the hepatocyte cell population by cell division
Synonyms (1)
"reduced hepatocyte proliferation" EXACT
Parents (2)
img abnormal hepatocyte physiology MP:0010080
img decreased cell proliferation MP:0000352
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img liver/biliary system phenotype MP:00053706img abnormal hepatocyte physiology MP:0010080
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img decreased cell proliferation MP:0000352
Genes (26)

Species:
human : 26
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanCCNDBP123582cyclin D-type binding-protein 1
Click here to display 32 evidence detail records.
HumanRAD5010111RAD50 homolog (S. cerevisiae)
Click here to display 32 evidence detail records.
HumanNR1I28856nuclear receptor subfamily 1, group I, member 2
Click here to display 32 evidence detail records.
HumanCUL4A8451cullin 4A
Click here to display 32 evidence detail records.
HumanXBP17494X-box binding protein 1
Click here to display 32 evidence detail records.
HumanSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
Click here to display 32 evidence detail records.
HumanSPTBN16711spectrin, beta, non-erythrocytic 1
Click here to display 32 evidence detail records.
HumanSLC20A16574solute carrier family 20 (phosphate transporter), member 1
Click here to display 32 evidence detail records.
HumanSEL1L6400sel-1 suppressor of lin-12-like (C. elegans)
Click here to display 32 evidence detail records.
HumanRXRA6256retinoid X receptor, alpha
Click here to display 32 evidence detail records.
HumanREG1B5968regenerating islet-derived 1 beta
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HumanPROX15629prospero homeobox 1
Click here to display 32 evidence detail records.
HumanNFE2L24780nuclear factor, erythroid 2-like 2
Click here to display 32 evidence detail records.
HumanMT1E4493metallothionein 1E
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HumanMGAT34248mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
Click here to display 32 evidence detail records.
HumanSMAD24087SMAD family member 2
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HumanJUN3725jun proto-oncogene
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HumanITIH43700inter-alpha-trypsin inhibitor heavy chain family, member 4
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HumanHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
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HumanHGF3082hepatocyte growth factor (hepapoietin A; scatter factor)
Click here to display 32 evidence detail records.
HumanFAH2184fumarylacetoacetate hydrolase (fumarylacetoacetase)
Click here to display 32 evidence detail records.
HumanERCC12067excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Click here to display 32 evidence detail records.
HumanCEBPA1050CCAAT/enhancer binding protein (C/EBP), alpha
Click here to display 32 evidence detail records.
HumanCDK21017cyclin-dependent kinase 2
Click here to display 32 evidence detail records.
HumanCAV1857caveolin 1, caveolae protein, 22kDa
Click here to display 32 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004001decreased hepatocyte proliferation0self