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Details
Link-It Detail - Jax Mouse Phenotype - abnormal glucagon secretion
Debug Stats
  • ### Total Build Time: 20 ms 16.932 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 382 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.025 KB
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  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=9 ms Completed: 9 ms rowSize= 8.046 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.165 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal glucagon secretion MP:0003565
Definition (1)
anomaly in the production or release of this hormone secreted by the alpha cells of the islets of Langerhans; it normally plays a role in regulation of blood glucose concentration, ketone metabolism, and other biochemical and physiological processes
Parents (3)
img abnormal pancreatic alpha cell physiology MP:0003563
img abnormal pancreas secretion MP:0002694
img abnormal glucose homeostasis MP:0002078
Children (2)
img increased glucagon secretion MP:0002710
img decreased glucagon secretion MP:0002711
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img endocrine/exocrine gland phenotype MP:00053797img abnormal pancreatic alpha cell physiology MP:0003563
img mammalian phenotype MP:0000001img endocrine/exocrine gland phenotype MP:00053796img abnormal pancreas secretion MP:0002694
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img abnormal glucose homeostasis MP:0002078
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanCADPS293664Ca++-dependent secretion activator 2
INFERRED
HumanCADPS8618Ca++-dependent secretion activator
INFERRED
HumanWFS17466Wolfram syndrome 1 (wolframin)
INFERRED
HumanTHRA7067thyroid hormone receptor, alpha
INFERRED
HumanSNAP256616synaptosomal-associated protein, 25kDa
INFERRED
HumanPCSK25126proprotein convertase subtilisin/kexin type 2
INFERRED
HumanNKX2-24821
INFERRED
HumanLEPR3953leptin receptor
INFERRED
HumanKCNJ113767potassium inwardly-rectifying channel, subfamily J, member 11
INFERRED
HumanPDX13651pancreatic and duodenal homeobox 1
INFERRED
HumanIL63569interleukin 6 (interferon, beta 2)
INFERRED
HumanGPER12852G protein-coupled estrogen receptor 1
INFERRED
HumanDBH1621dopamine beta-hydroxylase (dopamine beta-monooxygenase)
INFERRED
HumanCHRM31131cholinergic receptor, muscarinic 3
INFERRED
HumanCACNA1E777calcium channel, voltage-dependent, R type, alpha 1E subunit
img Jax MP, Pubmed Id: 15630454, MOUSE PHENOTYPE ID: MGI:106217
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0003565abnormal glucagon secretion0self