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Details
Link-It Detail - Jax Mouse Phenotype - decreased susceptibility to induced arthritis
Debug Stats
  • ### Total Build Time: 150 ms 28.378 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 418 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 462 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 199 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 1.504 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
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  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=149 ms Completed: 149 ms rowSize= 17.532 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.183 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
decreased susceptibility to induced arthritis MP:0003436
Definition (1)
less likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents
Synonyms (1)
"increased resistance to induced arthritis" EXACT
Parents (3)
img decreased susceptibility to induced joint inflammation MP:0003079
img decreased susceptibility to autoimmune disorder MP:0005351
img arthritis MP:0002993
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img skeleton phenotype MP:00053906img decreased susceptibility to induced joint inflammation MP:0003079
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img decreased susceptibility to induced joint inflammation MP:0003079
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img decreased susceptibility to autoimmune disorder MP:0005351
img mammalian phenotype MP:0000001img skeleton phenotype MP:00053906img arthritis MP:0002993
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img arthritis MP:0002993
Genes (57)

Species:
human : 57
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanRASGRP4115727RAS guanyl releasing protein 4
Click here to display 90 evidence detail records.
HumanPGLYRP2114770peptidoglycan recognition protein 2
Click here to display 90 evidence detail records.
HumanSYVN184447synovial apoptosis inhibitor 1, synoviolin
Click here to display 90 evidence detail records.
HumanTPSB264499tryptase beta 2 (gene/pseudogene)
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HumanNOD264127nucleotide-binding oligomerization domain containing 2
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HumanGPSM363940G-protein signaling modulator 3
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HumanLTB4R256413leukotriene B4 receptor 2
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HumanCLEC5A23601C-type lectin domain family 5, member A
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HumanADAMTS511096ADAM metallopeptidase with thrombospondin type 1 motif, 5
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HumanPGLYRP18993peptidoglycan recognition protein 1
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HumanKSR18844kinase suppressor of ras 1
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HumanTNFSF138741tumor necrosis factor (ligand) superfamily, member 13
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HumanNDST28509N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
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HumanCXCR47852chemokine (C-X-C motif) receptor 4
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HumanZAP707535zeta-chain (TCR) associated protein kinase 70kDa
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HumanTYROBP7305TYRO protein tyrosine kinase binding protein
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HumanTYK27297tyrosine kinase 2
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HumanTPSAB17177tryptase alpha/beta 1
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HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
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HumanTNF7124tumor necrosis factor
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HumanTLR47099toll-like receptor 4
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HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Click here to display 90 evidence detail records.
HumanPTGS15742prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Click here to display 90 evidence detail records.
HumanPTGER45734prostaglandin E receptor 4 (subtype EP4)
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HumanPLCG25336phospholipase C, gamma 2 (phosphatidylinositol-specific)
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XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0003436decreased susceptibility to induced arthritis0self