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Details
Link-It Detail - Jax Mouse Phenotype - decreased paired-pulse facilitation
Debug Stats
  • ### Total Build Time: 37 ms 14.780 KB
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  • Reload Stats
Jax Mouse Phenotype (1)
decreased paired-pulse facilitation MP:0002920
Definition (1)
reduction in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus
Synonyms (1)
"reduced PPF" EXACT
Parents (1)
img abnormal paired-pulse facilitation MP:0002918
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036316img abnormal paired-pulse facilitation MP:0002918
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanFBXL2084961F-box and leucine-rich repeat protein 20
Click here to display 35 evidence detail records.
HumanLYNX166004Ly6/neurotoxin 1
Click here to display 35 evidence detail records.
HumanRIMS122999regulating synaptic membrane exocytosis 1
Click here to display 35 evidence detail records.
HumanSYNGR19145synaptogyrin 1
Click here to display 35 evidence detail records.
HumanVDAC37419voltage-dependent anion channel 3
Click here to display 35 evidence detail records.
HumanVDAC17416voltage-dependent anion channel 1
Click here to display 35 evidence detail records.
HumanUCHL17345ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Click here to display 35 evidence detail records.
HumanSNAP256616synaptosomal-associated protein, 25kDa
Click here to display 35 evidence detail records.
HumanSCT6343secretin
Click here to display 35 evidence detail records.
HumanATXN16310ataxin 1
Click here to display 35 evidence detail records.
HumanMAPK95601mitogen-activated protein kinase 9
Click here to display 35 evidence detail records.
HumanGRM42914glutamate receptor, metabotropic 4
Click here to display 35 evidence detail records.
HumanGRIK42900glutamate receptor, ionotropic, kainate 4
Click here to display 35 evidence detail records.
HumanGRIK32899glutamate receptor, ionotropic, kainate 3
Click here to display 35 evidence detail records.
HumanGRIK22898glutamate receptor, ionotropic, kainate 2
Click here to display 35 evidence detail records.
HumanCHRM11128cholinergic receptor, muscarinic 1
Click here to display 35 evidence detail records.
HumanCAMK2A815calcium/calmodulin-dependent protein kinase II alpha
Click here to display 35 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002920decreased paired-pulse facilitation0self