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Details
Link-It Detail - Jax Mouse Phenotype - increased susceptibility to pharmacologically induced seizures
Debug Stats
  • ### Total Build Time: 314 ms 24.895 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 452 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 308 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 216 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 605 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.333 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=306 ms Completed: 306 ms rowSize= 17.666 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.199 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased susceptibility to pharmacologically induced seizures MP:0002906
Definition (1)
inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals; exhibit a lower threshold to induce seizure activity
Synonyms (1)
"decreased resistance to pharmacologically induced seizures" EXACT
Parents (1)
img abnormal seizure response to pharmacological agent MP:0000950
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036317img abnormal seizure response to pharmacological agent MP:0000950
img mammalian phenotype MP:0000001img behavior/neurological phenotype MP:00053867img abnormal seizure response to pharmacological agent MP:0000950
img mammalian phenotype MP:0000001img behavior/neurological phenotype MP:00053866img abnormal seizure response to pharmacological agent MP:0000950
Genes (74)

Species:
human : 74
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SpeciesGeneGeneIdGene NameEvidence
HumanSLC10A4201780solute carrier family 10, member 4
Click here to display 126 evidence detail records.
HumanARX170302aristaless related homeobox
Click here to display 126 evidence detail records.
HumanPRICKLE2166336prickle homolog 2 (Drosophila)
Click here to display 126 evidence detail records.
HumanEFHC1114327EF-hand domain (C-terminal) containing 1
Click here to display 126 evidence detail records.
HumanSLC12A557468solute carrier family 12 (potassium/chloride transporter), member 5
Click here to display 126 evidence detail records.
HumanRBFOX154715RNA binding protein, fox-1 homolog (C. elegans) 1
Click here to display 126 evidence detail records.
HumanGAL51083galanin/GMAP prepropeptide
Click here to display 126 evidence detail records.
HumanLHX626468LIM homeobox 6
Click here to display 126 evidence detail records.
HumanKCNH323416potassium voltage-gated channel, subfamily H (eag-related), member 3
Click here to display 126 evidence detail records.
HumanSZT223334seizure threshold 2 homolog (mouse)
Click here to display 126 evidence detail records.
HumanPLCB123236phospholipase C, beta 1 (phosphoinositide-specific)
Click here to display 126 evidence detail records.
HumanKLK811202kallikrein-related peptidase 8
Click here to display 126 evidence detail records.
HumanCIT11113citron (rho-interacting, serine/threonine kinase 21)
Click here to display 126 evidence detail records.
HumanAP3M210947adaptor-related protein complex 3, mu 2 subunit
Click here to display 126 evidence detail records.
HumanAKT310000v-akt murine thymoma viral oncogene homolog 3
Click here to display 126 evidence detail records.
HumanSLC12A69990solute carrier family 12 (potassium/chloride transporter), member 6
Click here to display 126 evidence detail records.
HumanCACNA2D29254calcium channel, voltage-dependent, alpha 2/delta subunit 2
Click here to display 126 evidence detail records.
HumanLGI19211leucine-rich, glioma inactivated 1
Click here to display 126 evidence detail records.
HumanBSN8927bassoon presynaptic cytomatrix protein
Click here to display 126 evidence detail records.
HumanCDK5R18851cyclin-dependent kinase 5, regulatory subunit 1 (p35)
Click here to display 126 evidence detail records.
HumanSYNGAP18831synaptic Ras GTPase activating protein 1
Click here to display 126 evidence detail records.
HumanNRP28828neuropilin 2
Click here to display 126 evidence detail records.
HumanBHLHE408553basic helix-loop-helix family, member e40
Click here to display 126 evidence detail records.
HumanCUL4B8450cullin 4B
Click here to display 126 evidence detail records.
HumanFZD98326frizzled family receptor 9
Click here to display 126 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002906increased susceptibility to pharmacologically induced seizures0self