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Details
Link-It Detail - Jax Mouse Phenotype - abnormal NMDA-mediated synaptic currents
Debug Stats
  • ### Total Build Time: 197 ms 18.991 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 260 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=29 ms Completed: 29 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=15 ms Completed: 15 ms rowSize= 600 bytes
  • CONCEPT_CHILDREN gt=14 ms Completed: 14 ms rowSize= 2.007 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=39 ms Completed: 39 ms rowSize= 1.591 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=91 ms Completed: 91 ms rowSize= 12.833 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.178 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal NMDA-mediated synaptic currents MP:0002888
Definition (1)
change in the measured amplitude, current density or duration of response to stimulation of NMDA receptors
Parents (1)
img abnormal glutamate-mediated receptor currents MP:0002886
Children (4)
img absence of NMDA-mediated synaptic currents MP:0001901
img reduced NMDA receptor mediated synaptic activity in barrel cortex MP:0001909
img reduced NMDA-mediated synaptic currents MP:0001902
img enhanced NMDA-mediated synaptic currents MP:0003234
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036317img abnormal glutamate-mediated receptor currents MP:0002886
Genes (24)

Species:
human : 24
SpeciesGeneGeneIdGene NameEvidence
HumanDLGAP358512discs, large (Drosophila) homolog-associated protein 3
INFERRED
HumanKIF1757576kinesin family member 17
INFERRED
HumanVPS3555737vacuolar protein sorting 35 homolog (S. cerevisiae)
INFERRED
HumanMAPK8IP223542mitogen-activated protein kinase 8 interacting protein 2
Click here to display 20 evidence detail records.
HumanMAPK8IP19479mitogen-activated protein kinase 8 interacting protein 1
Click here to display 20 evidence detail records.
HumanNRXN29379neurexin 2
INFERRED
HumanLGI19211leucine-rich, glioma inactivated 1
INFERRED
HumanCCNE29134cyclin E2
INFERRED
HumanWASF18936WAS protein family, member 1
Click here to display 20 evidence detail records.
HumanRGS98787regulator of G-protein signaling 9
Click here to display 20 evidence detail records.
HumanSLC6A96536solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Click here to display 20 evidence detail records.
HumanSERPINE25270serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
INFERRED
HumanGRIN2C2905glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Click here to display 20 evidence detail records.
HumanGRIN2B2904glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Click here to display 20 evidence detail records.
HumanGRIN2A2903glutamate receptor, ionotropic, N-methyl D-aspartate 2A
INFERRED
HumanGRIN12902glutamate receptor, ionotropic, N-methyl D-aspartate 1
Click here to display 20 evidence detail records.
HumanGRIK42900glutamate receptor, ionotropic, kainate 4
INFERRED
HumanFOSB2354FBJ murine osteosarcoma viral oncogene homolog B
INFERRED
HumanFABP72173fatty acid binding protein 7, brain
INFERRED
HumanEPS82059epidermal growth factor receptor pathway substrate 8
INFERRED
HumanEMX12016empty spiracles homeobox 1
INFERRED
HumanDLG41742discs, large homolog 4 (Drosophila)
Click here to display 20 evidence detail records.
HumanDAPK11612death-associated protein kinase 1
INFERRED
HumanCACNB3784calcium channel, voltage-dependent, beta 3 subunit
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002888abnormal NMDA-mediated synaptic currents0self