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Details
Link-It Detail - Jax Mouse Phenotype - abnormal macrophage antigen presentation
Debug Stats
  • ### Total Build Time: 19 ms 16.641 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 255 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 201 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.026 KB
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 611 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 4.257 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 8.595 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.178 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal macrophage antigen presentation MP:0002454
Definition (1)
anomaly in the ability of macrophage phagocytic cells to process and present antigen to T lymphocytes
Synonyms (1)
"macrophage antigen presentation dysfunction" EXACT
Parents (2)
img abnormal antigen presentation MP:0001835
img abnormal macrophage physiology MP:0002451
Children (1)
img abnormal MHC II cell surface expression on macrophages MP:0005040
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal antigen presentation MP:0001835
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal macrophage physiology MP:0002451
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal macrophage physiology MP:0002451
Genes (8)

Species:
human : 8
SpeciesGeneGeneIdGene NameEvidence
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
INFERRED
HumanRFX55993regulatory factor X, 5 (influences HLA class II expression)
INFERRED
HumanCIITA4261class II, major histocompatibility complex, transactivator
INFERRED
HumanIFNG3458interferon, gamma
INFERRED
HumanHLA-DQB13119
img Jax MP, Pubmed Id: 22624878, MOUSE PHENOTYPE ID: MGI:96897
img Jax MP, Pubmed Id: 7547694, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 11911823, MOUSE PHENOTYPE ID: MGI:95498
HumanHLA-DQA13117
INFERRED
HumanFCGR1A2209Fc fragment of IgG, high affinity Ia, receptor (CD64)
img Jax MP, Pubmed Id: 7547694, MOUSE PHENOTYPE ID: MGI:103070
img Jax MP, Pubmed Id: 11911823, MOUSE PHENOTYPE ID: MGI:95498
img Jax MP, Pubmed Id: 22624878, MOUSE PHENOTYPE ID: MGI:96897
HumanCSF21437colony stimulating factor 2 (granulocyte-macrophage)
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002454abnormal macrophage antigen presentation0self