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Details
Link-It Detail - Jax Mouse Phenotype - abnormal lymph node secondary follicle morphology
Debug Stats
  • ### Total Build Time: 28 ms 56.555 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 426 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 524 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 599 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.062 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.589 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=18 ms Completed: 18 ms rowSize= 51.060 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.187 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal lymph node secondary follicle morphology MP:0002346
Definition (1)
any structural anomaly of a lymph node primary follicle that has undergone antigenic challenge and is characterized by a ring of concentrically packed B lymphocytes surrounding a germinal center, which contains proliferating B cells, and a mantle area that contains nondividing B cells and some helper T cells with macrophages and follicular dendritic cells interspersed
Parents (1)
img abnormal lymph node B cell domain morphology MP:0002344
Children (2)
img abnormal lymph node germinal center morphology MP:0008522
img abnormal lymph node follicular mantle morphology MP:0010774
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal lymph node B cell domain morphology MP:0002344
Genes (27)

Species:
human : 27
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanUNC13D201294unc-13 homolog D (C. elegans)
INFERRED
HumanRC3H1149041ring finger and CCCH-type domains 1
INFERRED
HumanKLHL689857kelch-like family member 6
INFERRED
HumanHR55806hair growth associated
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 16887989, MOUSE PHENOTYPE ID: MGI:1342293
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:1314883
img Jax MP, Pubmed Id: 7744000, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 11468173, MOUSE PHENOTYPE ID: MGI:98278
img Jax MP, Pubmed Id: 7640630, MOUSE PHENOTYPE ID: MGI:96223
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:107656
HumanIL21R50615interleukin 21 receptor
INFERRED
HumanLAT27040linker for activation of T cells
img Jax MP, Pubmed Id: 7744000, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 11468173, MOUSE PHENOTYPE ID: MGI:98278
img Jax MP, Pubmed Id: 7640630, MOUSE PHENOTYPE ID: MGI:96223
img Jax MP, Pubmed Id: 16887989, MOUSE PHENOTYPE ID: MGI:1342293
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:1314883
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:107656
HumanRRAS222800related RAS viral (r-ras) oncogene homolog 2
INFERRED
HumanCXCL1310563chemokine (C-X-C motif) ligand 13
INFERRED
HumanBHLHE408553basic helix-loop-helix family, member e40
INFERRED
HumanTRAF27186TNF receptor-associated factor 2
INFERRED
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 7640630, MOUSE PHENOTYPE ID: MGI:96223
img Jax MP, Pubmed Id: 16887989, MOUSE PHENOTYPE ID: MGI:1342293
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 11468173, MOUSE PHENOTYPE ID: MGI:98278
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:1314883
img Jax MP, Pubmed Id: 7744000, MOUSE PHENOTYPE ID: MGI:88373
HumanTNF7124tumor necrosis factor
INFERRED
HumanSELE6401selectin E
img Jax MP, Pubmed Id: 7640630, MOUSE PHENOTYPE ID: MGI:96223
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 11468173, MOUSE PHENOTYPE ID: MGI:98278
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 7744000, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 16887989, MOUSE PHENOTYPE ID: MGI:1342293
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:1314883
HumanPRKCD5580protein kinase C, delta
INFERRED
HumanPOU2AF15450POU class 2 associating factor 1
INFERRED
HumanNFKB24791nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
INFERRED
HumanIRF43662interferon regulatory factor 4
INFERRED
HumanINPP5D3635inositol polyphosphate-5-phosphatase, 145kDa
INFERRED
HumanIFNG3458interferon, gamma
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 16887989, MOUSE PHENOTYPE ID: MGI:1342293
img Jax MP, Pubmed Id: 7640630, MOUSE PHENOTYPE ID: MGI:96223
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:1314883
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 7744000, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 11468173, MOUSE PHENOTYPE ID: MGI:98278
HumanCCR71236chemokine (C-C motif) receptor 7
INFERRED
HumanCEBPB1051CCAAT/enhancer binding protein (C/EBP), beta
img Jax MP, Pubmed Id: 7640630, MOUSE PHENOTYPE ID: MGI:96223
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:1314883
img Jax MP, Pubmed Id: 16887989, MOUSE PHENOTYPE ID: MGI:1342293
img Jax MP, Pubmed Id: 11468173, MOUSE PHENOTYPE ID: MGI:98278
img Jax MP, Pubmed Id: 7744000, MOUSE PHENOTYPE ID: MGI:88373
HumanCDKN2B1030cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 7744000, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 10880462, MOUSE PHENOTYPE ID: MGI:104737
img Jax MP, Pubmed Id: 9647244, MOUSE PHENOTYPE ID: MGI:1314883
img Jax MP, Pubmed Id: 16887989, MOUSE PHENOTYPE ID: MGI:1342293
img Jax MP, Pubmed Id: 11468173, MOUSE PHENOTYPE ID: MGI:98278
img Jax MP, Pubmed Id: 7640630, MOUSE PHENOTYPE ID: MGI:96223
HumanCD40LG959CD40 ligand
INFERRED
HumanCD40958CD40 molecule, TNF receptor superfamily member 5
INFERRED
HumanCD37951CD37 molecule
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002346abnormal lymph node secondary follicle morphology0self