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Details
Link-It Detail - Jax Mouse Phenotype - abnormal antigen presentation via MHC class I
Debug Stats
  • ### Total Build Time: 29 ms 33.382 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 418 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 316 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 237 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 584 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 1.531 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 1.574 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=26 ms Completed: 26 ms rowSize= 27.431 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.183 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal antigen presentation via MHC class I MP:0001836
Definition (1)
anomaly in the process by which peptide, bound to major histocompatibility complex class I, is presented to lymphocytes at the surface of antigen presenting cells
Synonyms (1)
"inability to present cytosolic antigens to Class-I restricted cytotoxic T cells" EXACT
Parents (1)
img abnormal antigen presentation MP:0001835
Children (3)
img defective intracellular transport of class I molecules MP:0001838
img abnormal level of surface class I molecules MP:0001839
img defective assembly of class I molecules MP:0001837
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal antigen presentation MP:0001835
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
img Jax MP, Pubmed Id: 16415873, MOUSE PHENOTYPE ID: MGI:1859307
img Jax MP, Pubmed Id: 17128277
img Jax MP, Pubmed Id: 16299505
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:98483
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 17128277, MOUSE PHENOTYPE ID: MGI:1933403
img Jax MP, Pubmed Id: 10981964, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 16299505, MOUSE PHENOTYPE ID: MGI:1933403
HumanERAP151752endoplasmic reticulum aminopeptidase 1
img Jax MP, Pubmed Id: 16415873, MOUSE PHENOTYPE ID: MGI:1859307
img Jax MP, Pubmed Id: 10981964, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 16299505, MOUSE PHENOTYPE ID: MGI:1933403
img Jax MP, Pubmed Id: 16299505
img Jax MP, Pubmed Id: 17128277, MOUSE PHENOTYPE ID: MGI:1933403
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:98483
img Jax MP, Pubmed Id: 17128277
HumanTPP27174tripeptidyl peptidase II
INFERRED
HumanTAPBP6892TAP binding protein (tapasin)
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:98483
img Jax MP, Pubmed Id: 16415873, MOUSE PHENOTYPE ID: MGI:1859307
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 10981964, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 16299505, MOUSE PHENOTYPE ID: MGI:1933403
img Jax MP, Pubmed Id: 16299505
img Jax MP, Pubmed Id: 17128277
img Jax MP, Pubmed Id: 17128277, MOUSE PHENOTYPE ID: MGI:1933403
HumanTAP16890transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
img Jax MP, Pubmed Id: 17128277, MOUSE PHENOTYPE ID: MGI:1933403
img Jax MP, Pubmed Id: 16415873, MOUSE PHENOTYPE ID: MGI:1859307
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 10973281, MOUSE PHENOTYPE ID: MGI:98483
img Jax MP, Pubmed Id: 10981964, MOUSE PHENOTYPE ID: MGI:1201689
img Jax MP, Pubmed Id: 17128277
img Jax MP, Pubmed Id: 16299505, MOUSE PHENOTYPE ID: MGI:1933403
img Jax MP, Pubmed Id: 16299505
HumanSTAT26773signal transducer and activator of transcription 2, 113kDa
INFERRED
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
INFERRED
HumanPSME25721proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
INFERRED
HumanPSMB85696proteasome (prosome, macropain) subunit, beta type, 8
INFERRED
HumanPRKDC5591protein kinase, DNA-activated, catalytic polypeptide
INFERRED
HumanB2M567beta-2-microglobulin
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0001836abnormal antigen presentation via MHC class I0self