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Details
Link-It Detail - Jax Mouse Phenotype - hyperkeratosis
Debug Stats
  • ### Total Build Time: 866 ms 22.066 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 356 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 255 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 181 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 600 bytes
  • CONCEPT_CHILDREN gt=10 ms Completed: 10 ms rowSize= 1,021 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=13 ms Completed: 13 ms rowSize= 1.587 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=816 ms Completed: 816 ms rowSize= 16.826 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
hyperkeratosis MP:0001242
Definition (1)
increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis
Synonyms (1)
"thicker cornified layer" EXACT
Parents (1)
img abnormal epidermis stratum corneum morphology MP:0001240
Children (2)
img parakeratosis MP:0003427
img orthokeratosis MP:0009675
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img integument phenotype MP:00107716img abnormal epidermis stratum corneum morphology MP:0001240
Genes (81)

Species:
human : 81
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SpeciesGeneGeneIdGene NameEvidence
HumanGPR89A653519G protein-coupled receptor 89A
Click here to display 188 evidence detail records.
HumanCERS3204219ceramide synthase 3
Click here to display 188 evidence detail records.
HumanDSG4147409desmoglein 4
Click here to display 188 evidence detail records.
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
Click here to display 188 evidence detail records.
HumanMOB1B92597MOB kinase activator 1B
INFERRED
HumanDGAT284649diacylglycerol O-acyltransferase 2
INFERRED
HumanNFKBIZ64332nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Click here to display 188 evidence detail records.
HumanSAV160485salvador homolog 1 (Drosophila)
INFERRED
HumanALOXE359344arachidonate lipoxygenase 3
Click here to display 188 evidence detail records.
HumanTTC7A57217tetratricopeptide repeat domain 7A
Click here to display 188 evidence detail records.
HumanHR55806hair growth associated
Click here to display 188 evidence detail records.
HumanZDHHC1354503zinc finger, DHHC-type containing 13
Click here to display 188 evidence detail records.
HumanRIPK454101receptor-interacting serine-threonine kinase 4
INFERRED
HumanGPR89B51463G protein-coupled receptor 89B
Click here to display 188 evidence detail records.
HumanABHD551099abhydrolase domain containing 5
Click here to display 188 evidence detail records.
HumanFOXP350943forkhead box P3
INFERRED
HumanNSDHL50814NAD(P) dependent steroid dehydrogenase-like
Click here to display 188 evidence detail records.
HumanGRHL129841grainyhead-like 1 (Drosophila)
Click here to display 188 evidence detail records.
HumanTBK129110TANK-binding kinase 1
Click here to display 188 evidence detail records.
HumanIL36RN26525interleukin 36 receptor antagonist
Click here to display 188 evidence detail records.
HumanABCA1226154ATP-binding cassette, sub-family A (ABC1), member 12
Click here to display 188 evidence detail records.
HumanLRIG126018leucine-rich repeats and immunoglobulin-like domains 1
Click here to display 188 evidence detail records.
HumanPOFUT123509protein O-fucosyltransferase 1
Click here to display 188 evidence detail records.
HumanPKP311187plakophilin 3
INFERRED
HumanSPINK511005serine peptidase inhibitor, Kazal type 5
Click here to display 188 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0001242hyperkeratosis0self