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Details
Link-It Detail - Jax Mouse Phenotype - abnormal midbrain morphology
Debug Stats
  • ### Total Build Time: 203 ms 26.376 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 384 bytes
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  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 3.816 KB
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  • CONCEPT_GENES gt=197 ms Completed: 197 ms rowSize= 16.392 KB
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Jax Mouse Phenotype (1)
abnormal midbrain morphology MP:0000897
Definition (1)
any structural anomaly associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes
Synonyms (1)
"abnormal mesencephalon morphology" EXACT
Parents (2)
img abnormal brainstem morphology MP:0005277
img abnormal brain morphology MP:0002152
Children (8)
img abnormal substantia nigra morphology MP:0000836
img abnormal tegmentum morphology MP:0006100
img abnormal trigeminal V mesencephalic nucleus morphology MP:0000906
img abnormal oculomotor nucleus morphology MP:0004280
img abnormal cerebral aqueduct morphology MP:0005537
img midbrain hyperplasia MP:0000898
img abnormal pretectal region morphology MP:0009637
img abnormal midbrain roof plate morphology MP:0006103
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036316img abnormal brainstem morphology MP:0005277
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036315img abnormal brain morphology MP:0002152
Genes (104)

Species:
human : 104
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SpeciesGeneGeneIdGene NameEvidence
HumanPIKFYVE200576phosphoinositide kinase, FYVE finger containing
Click here to display 108 evidence detail records.
HumanKDM2B84678lysine (K)-specific demethylase 2B
Click here to display 108 evidence detail records.
HumanTFAP2D83741transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
INFERRED
HumanFUZ80199fuzzy planar cell polarity protein
Click here to display 108 evidence detail records.
HumanWLS79971wntless homolog (Drosophila)
Click here to display 108 evidence detail records.
HumanNPAS364067neuronal PAS domain protein 3
INFERRED
HumanNEUROD458158neuronal differentiation 4
INFERRED
HumanVANGL257216VANGL planar cell polarity protein 2
Click here to display 108 evidence detail records.
HumanPDSS257107prenyl (decaprenyl) diphosphate synthase, subunit 2
Click here to display 108 evidence detail records.
HumanHHAT55733hedgehog acyltransferase
Click here to display 108 evidence detail records.
HumanVAC1455697Vac14 homolog (S. cerevisiae)
Click here to display 108 evidence detail records.
HumanSTRBP55342spermatid perinuclear RNA binding protein
INFERRED
HumanFBXW755294F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
INFERRED
HumanMKS154903Meckel syndrome, type 1
INFERRED
HumanUCHL551377ubiquitin carboxyl-terminal hydrolase L5
Click here to display 108 evidence detail records.
HumanLEF151176lymphoid enhancer-binding factor 1
INFERRED
HumanRAX30062retina and anterior neural fold homeobox
Click here to display 108 evidence detail records.
HumanHIPK228996homeodomain interacting protein kinase 2
INFERRED
HumanFOXB127023forkhead box B1
Click here to display 108 evidence detail records.
HumanDPCD25911deleted in primary ciliary dyskinesia homolog (mouse)
INFERRED
HumanKAT6B23522K(lysine) acetyltransferase 6B
INFERRED
HumanSUZ1223512SUZ12 polycomb repressive complex 2 subunit
INFERRED
HumanMYCBP223077MYC binding protein 2, E3 ubiquitin protein ligase
Click here to display 108 evidence detail records.
HumanCIT11113citron (rho-interacting, serine/threonine kinase 21)
Click here to display 108 evidence detail records.
HumanATG710533autophagy related 7
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0000897abnormal midbrain morphology0self