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Details
Link-It Detail - Jax Mouse Phenotype - abnormal mast cell morphology
Debug Stats
  • ### Total Build Time: 37 ms 25.058 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 386 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 343 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 586 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 2.870 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.274 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 15.317 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.167 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal mast cell morphology MP:0000359
Definition (1)
any structural anomaly of a cell that is found in almost all tissues, containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation
Parents (1)
img abnormal granulocyte morphology MP:0002441
Children (6)
img decreased mast cell number MP:0000336
img decreased mast cell protease storage MP:0000361
img decreased mast cell histamine storage MP:0000362
img increased mast cell number MP:0000324
img abnormal dermal mast cell morphology MP:0008020
img abnormal mast cell differentiation MP:0005462
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal granulocyte morphology MP:0002441
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal granulocyte morphology MP:0002441
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal granulocyte morphology MP:0002441
Genes (38)

Species:
human : 38
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSPRED1161742sprouty-related, EVH1 domain containing 1
INFERRED
HumanDSG4147409desmoglein 4
Click here to display 18 evidence detail records.
HumanNFATC2IP84901nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
INFERRED
HumanTPSB264499tryptase beta 2 (gene/pseudogene)
INFERRED
HumanCHST1551363carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
Click here to display 18 evidence detail records.
HumanRABGEF127342RAB guanine nucleotide exchange factor (GEF) 1
Click here to display 18 evidence detail records.
HumanAGR210551anterior gradient 2
INFERRED
HumanGAB29846GRB2-associated binding protein 2
INFERRED
HumanMAP3K149020mitogen-activated protein kinase kinase kinase 14
INFERRED
HumanNDST28509N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
Click here to display 18 evidence detail records.
HumanWAS7454Wiskott-Aldrich syndrome
Click here to display 18 evidence detail records.
HumanTPSAB17177tryptase alpha/beta 1
INFERRED
HumanSTAT66778signal transducer and activator of transcription 6, interleukin-4 induced
Click here to display 18 evidence detail records.
HumanSTAT5B6777signal transducer and activator of transcription 5B
INFERRED
HumanSTAT5A6776signal transducer and activator of transcription 5A
Click here to display 18 evidence detail records.
HumanSELP6403selectin P (granule membrane protein 140kDa, antigen CD62)
INFERRED
HumanSELE6401selectin E
INFERRED
HumanSRGN5552serglycin
Click here to display 18 evidence detail records.
HumanPLA2G4A5321phospholipase A2, group IVA (cytosolic, calcium-dependent)
INFERRED
HumanMITF4286microphthalmia-associated transcription factor
INFERRED
HumanKITLG4254KIT ligand
INFERRED
HumanMCL14170myeloid cell leukemia sequence 1 (BCL2-related)
INFERRED
HumanLYN4067v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
INFERRED
HumanLMO24005LIM domain only 2 (rhombotin-like 1)
Click here to display 18 evidence detail records.
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0000359abnormal mast cell morphology0self