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Details
Link-It Detail - Jax Mouse Phenotype - abnormal heart looping
Debug Stats
  • ### Total Build Time: 138 ms 21.611 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 372 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 388 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 581 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.477 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.579 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=129 ms Completed: 129 ms rowSize= 15.758 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal heart looping MP:0000269
Definition (1)
any anomaly in the characteristic morphogenetic movements where the primitive heart tube loops asymmetrically during early development; this looping brings the primitive heart chambers into alignment preceding their future integration
Synonyms (1)
"abnormal looping morphogenesis" BROAD
Parents (1)
img abnormal heart development MP:0000267
Children (3)
img delayed heart looping MP:0009328
img abnormal direction of heart looping MP:0004252
img failure of heart looping MP:0004251
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053856img abnormal heart development MP:0000267
Genes (104)

Species:
human : 104
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Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCFC1B653275cripto, FRL-1, cryptic family 1B
INFERRED
HumanDAND5199699DAN domain family member 5, BMP antagonist
INFERRED
HumanRDH10157506retinol dehydrogenase 10 (all-trans)
Click here to display 71 evidence detail records.
HumanTTBK2146057tau tubulin kinase 2
INFERRED
HumanDISP184976dispatched homolog 1 (Drosophila)
Click here to display 71 evidence detail records.
HumanCCM283605cerebral cavernous malformation 2
INFERRED
HumanDYNC2H179659dynein, cytoplasmic 2, heavy chain 1
INFERRED
HumanMYL758498myosin, light chain 7, regulatory
Click here to display 71 evidence detail records.
HumanOVOL258495ovo-like 2 (Drosophila)
Click here to display 71 evidence detail records.
HumanWDR3557539WD repeat domain 35
INFERRED
HumanMIB157534mindbomb E3 ubiquitin protein ligase 1
Click here to display 71 evidence detail records.
HumanVANGL257216VANGL planar cell polarity protein 2
Click here to display 71 evidence detail records.
HumanTBX2057057T-box 20
INFERRED
HumanCFC155997cripto, FRL-1, cryptic family 1
INFERRED
HumanMESP155897mesoderm posterior 1 homolog (mouse)
Click here to display 71 evidence detail records.
HumanIFT12255764intraflagellar transport 122 homolog (Chlamydomonas)
INFERRED
HumanIFT5755081intraflagellar transport 57 homolog (Chlamydomonas)
INFERRED
HumanMKS154903Meckel syndrome, type 1
Click here to display 71 evidence detail records.
HumanSUFU51684suppressor of fused homolog (Drosophila)
INFERRED
HumanDYNC2LI151626dynein, cytoplasmic 2, light intermediate chain 1
INFERRED
HumanDLL128514delta-like 1 (Drosophila)
INFERRED
HumanINTU27152inturned planar cell polarity protein
Click here to display 71 evidence detail records.
HumanINVS27130inversin
INFERRED
HumanIFT17226160intraflagellar transport 172 homolog (Chlamydomonas)
INFERRED
HumanC2CD326005C2 calcium-dependent domain containing 3
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0000269abnormal heart looping0self