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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating LDL cholesterol level
Debug Stats
  • ### Total Build Time: 381 ms 27.438 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 343 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 189 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=14 ms Completed: 14 ms rowSize= 1.048 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=79 ms Completed: 79 ms rowSize= 7.037 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=276 ms Completed: 276 ms rowSize= 17.097 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased circulating LDL cholesterol level MP:0000182
Definition (1)
greater amount in the blood of the lipoprotein:cholesterol complex that transports cholesterol out of the arteries and around the body, for use by various tissues in normal bodily functions
Synonyms (1)
"increased LDL cholesterol level" EXACT
Parents (2)
img increased circulating cholesterol level MP:0005178
img abnormal circulating LDL cholesterol level MP:0000181
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img increased circulating cholesterol level MP:0005178
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img increased circulating cholesterol level MP:0005178
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating LDL cholesterol level MP:0000181
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating LDL cholesterol level MP:0000181
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal circulating LDL cholesterol level MP:0000181
Genes (35)

Species:
human : 35
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanFFAR4338557free fatty acid receptor 4
Click here to display 104 evidence detail records.
HumanPCSK9255738proprotein convertase subtilisin/kexin type 9
Click here to display 104 evidence detail records.
HumanSLC2A829988solute carrier family 2 (facilitated glucose transporter), member 8
Click here to display 104 evidence detail records.
HumanLDLRAP126119low density lipoprotein receptor adaptor protein 1
Click here to display 104 evidence detail records.
HumanSIRT323410sirtuin 3
Click here to display 104 evidence detail records.
HumanNR1H310062nuclear receptor subfamily 1, group H, member 3
Click here to display 104 evidence detail records.
HumanNR1D19572nuclear receptor subfamily 1, group D, member 1
Click here to display 104 evidence detail records.
HumanLIPG9388lipase, endothelial
Click here to display 104 evidence detail records.
HumanHDAC38841histone deacetylase 3
Click here to display 104 evidence detail records.
HumanSLC3A16519solute carrier family 3 (amino acid transporter heavy chain), member 1
Click here to display 104 evidence detail records.
HumanSCP26342sterol carrier protein 2
Click here to display 104 evidence detail records.
HumanPRKCI5584protein kinase C, iota
Click here to display 104 evidence detail records.
HumanPON15444paraoxonase 1
Click here to display 104 evidence detail records.
HumanPLTP5360phospholipid transfer protein
Click here to display 104 evidence detail records.
HumanOLR14973oxidized low density lipoprotein (lectin-like) receptor 1
Click here to display 104 evidence detail records.
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
Click here to display 104 evidence detail records.
HumanNOS14842nitric oxide synthase 1 (neuronal)
Click here to display 104 evidence detail records.
HumanMECP24204methyl CpG binding protein 2 (Rett syndrome)
Click here to display 104 evidence detail records.
HumanLIPC3990lipase, hepatic
Click here to display 104 evidence detail records.
HumanLIPA3988lipase A, lysosomal acid, cholesterol esterase
Click here to display 104 evidence detail records.
HumanLEPR3953leptin receptor
Click here to display 104 evidence detail records.
HumanLEP3952leptin
Click here to display 104 evidence detail records.
HumanLDLR3949low density lipoprotein receptor
Click here to display 104 evidence detail records.
HumanINS3630insulin
Click here to display 104 evidence detail records.
HumanGPR122835G protein-coupled receptor 12
Click here to display 104 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0000182increased circulating LDL cholesterol level0self