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Details
Link-It Detail - Pathway - Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
Debug Stats
  • ### Total Build Time: 34 ms 17.208 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 272 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_DEFINITION gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=29 ms Completed: 29 ms rowSize= 15.633 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.136 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Pathway (1)
Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. sa_mmp_cytokine_connection
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1363982
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1363984
HumanTNF7124tumor necrosis factor
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0812246
HumanTGFB27042transforming growth factor, beta 2
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1336621
HumanTGFB17040transforming growth factor, beta 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1366557
HumanSPN6693sialophorin
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1420364
HumanSELL6402selectin L
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1335808
HumanIL6R3570interleukin 6 receptor
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1416409
HumanIL1B3553interleukin 1, beta
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1334112
HumanFCGR3A2214Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1414555
HumanACE1636angiotensin I converting enzyme
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1413931
HumanCSF11435colony stimulating factor 1 (macrophage)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332789
HumanCD44960CD44 molecule (Indian blood group)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332712
HumanTNFSF8944tumor necrosis factor (ligand) superfamily, member 8
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1420820
HumanTNFRSF8943tumor necrosis factor receptor superfamily, member 8
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1456796
XRefs (1)

XRef Types:
pathway : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
PATHWAYimg sa_mmp_cytokine_connectionCytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.0self