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GATACA
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Details
Link-It Detail - Pathway - Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
Debug Stats
  • ### Total Build Time: 13 ms 27.601 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 309 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_DEFINITION gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 25.951 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.174 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Pathway (1)
Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. sa_b_cell_receptor_complexes
Genes (24)

Species:
human : 24
SpeciesGeneGeneIdGene NameEvidence
HumanBLNK29760B-cell linker
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332420
HumanMAPK8IP323162mitogen-activated protein kinase 8 interacting protein 3
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1417026
HumanVAV310451vav 3 guanine nucleotide exchange factor
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1336927
HumanVAV27410vav 2 guanine nucleotide exchange factor
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0812239
HumanVAV17409vav 1 guanine nucleotide exchange factor
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1336926
HumanSYK6850spleen tyrosine kinase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1335892
HumanSOS16654son of sevenless homolog 1 (Drosophila)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1420314
HumanSHC16464SHC (Src homology 2 domain containing) transforming protein 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1335821
HumanRPS6KA36197ribosomal protein S6 kinase, 90kDa, polypeptide 3
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1419744
HumanRPS6KA16195ribosomal protein S6 kinase, 90kDa, polypeptide 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1419742
HumanRAC15879ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1419227
HumanMAP2K15604mitogen-activated protein kinase kinase 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1334474
HumanMAPK35595mitogen-activated protein kinase 3
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1366765
HumanMAPK15594mitogen-activated protein kinase 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1366882
HumanPAPPA5069pregnancy-associated plasma protein A, pappalysin 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1442932
HumanMAP3K14214mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1367675
HumanLYN4067v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0812307
HumanJUN3725jun proto-oncogene
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0162508
HumanHRAS3265Harvey rat sarcoma viral oncogene homolog
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0079471
HumanGRB22885growth factor receptor-bound protein 2
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1333707
HumanFOS2353FBJ murine osteosarcoma viral oncogene homolog
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0087140
HumanELK12002ELK1, member of ETS oncogene family
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0812446
HumanATF21386activating transcription factor 2
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332119
HumanBCR613breakpoint cluster region
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0812385
XRefs (1)

XRef Types:
pathway : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
PATHWAYimg sa_b_cell_receptor_complexesAntigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.0self