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Details
Link-It Detail - Human Phenotype - Abnormality of prothrombin
Debug Stats
  • ### Total Build Time: 23 ms 13.491 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 201 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 299 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 459 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.089 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 2.113 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 8.188 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.021 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Human Phenotype (1)
Abnormality of prothrombin HP:0012200
Definition (1)
An anomaly of clotting factor II, which is known as prothrombin, a vitamin K-dependent proenzyme that functions in the blood coagulation cascade.
Parents (1)
img Abnormality of the coagulation cascade HP:0003256
Children (3)
img Reduced prothrombin consumption HP:0003337
img Reduced prothrombin activity HP:0012201
img Prolonged prothrombin time HP:0008151
Ancestral Roots
RootRoot Plus OneDepthParent
img All HP:0000001img Phenotypic abnormality HP:00001186img Abnormality of the coagulation cascade HP:0003256
img All HP:0000001img Phenotypic abnormality HP:00001185img Abnormality of the coagulation cascade HP:0003256
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanVKORC179001vitamin K epoxide reductase complex, subunit 1
img HP RolledUp, OMIM ID: 607473
HumanHPLH127259hemophagocytic lymphohistiocytosis 1
img HP RolledUp, OMIM ID: 267700
HumanPRF15551perforin 1 (pore forming protein)
img HP RolledUp, OMIM ID: 603553
HumanPMM25373phosphomannomutase 2
img HP RolledUp, OMIM ID: 212065
HumanHLA-DQB13119
img HP RolledUp, OMIM ID: 212750
HumanHLA-DQA13117
img HP RolledUp, OMIM ID: 212750
HumanGGCX2677gamma-glutamyl carboxylase
img HP RolledUp, OMIM ID: 610842
HumanF112160coagulation factor XI
img HP RolledUp, OMIM ID: 264900
HumanF102159coagulation factor X
img HP RolledUp, OMIM ID: 227600
HumanF22147coagulation factor II (thrombin)
img HP RolledUp, OMIM ID: 613679
XRefs (1)

XRef Types:
hp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
HPimg HP:0012200Abnormality of prothrombin0self