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Details
Link-It Detail - Human Phenotype - Abnormality of natural killer cells
Debug Stats
  • ### Total Build Time: 24 ms 10.869 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 210 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 453 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 447 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 462 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 3.019 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=6 ms Completed: 6 ms rowSize= 5.142 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.029 KB
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  • Reload Stats
Human Phenotype (1)
Abnormality of natural killer cells HP:0012176
Definition (1)
An anomaly of the `natural killer cell` (CL:0000623), which is a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.
Parents (1)
img Abnormality of lymphocytes HP:0004332
Children (1)
img Abnormal natural killer cell physiology HP:0012177
Ancestral Roots
RootRoot Plus OneDepthParent
img All HP:0000001img Phenotypic abnormality HP:00001185img Abnormality of lymphocytes HP:0004332
img All HP:0000001img Phenotypic abnormality HP:00001186img Abnormality of lymphocytes HP:0004332
img All HP:0000001img Phenotypic abnormality HP:00001187img Abnormality of lymphocytes HP:0004332
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanUNC13D201294unc-13 homolog D (C. elegans)
img HP RolledUp, OMIM ID: 608898
HumanWIPF17456WAS/WASL interacting protein family, member 1
img HP RolledUp, OMIM ID: 614493
HumanSTXBP26813syntaxin binding protein 2
img HP RolledUp, OMIM ID: 613101
HumanSH2D1A4068SH2 domain containing 1A
img HP RolledUp, OMIM ID: 308240
HumanGATA22624GATA binding protein 2
img HP TAS, OMIM ID: 614172
HumanXIAP331X-linked inhibitor of apoptosis
img HP RolledUp, OMIM ID: 308240
XRefs (1)

XRef Types:
hp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
HPimg HP:0012176Abnormality of natural killer cells0self