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Details
Link-It Detail - Human Phenotype - Abnormality of methionine metabolism
Debug Stats
  • ### Total Build Time: 18 ms 19.043 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 211 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 216 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 820 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.077 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 4.032 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=9 ms Completed: 9 ms rowSize= 11.541 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.030 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Human Phenotype (1)
Abnormality of methionine metabolism HP:0010901
Definition (1)
An abnormality of `methionine metabolic process` (GO:0006555).
Parents (2)
img Abnormality of sulfur amino acid metabolism HP:0004339
img Abnormality of aspartate family amino acid metabolism HP:0010899
Children (3)
img Decreased methionine synthase activity HP:0003524
img Hypermethioninemia HP:0003235
img Hypomethioninemia HP:0003658
Ancestral Roots
RootRoot Plus OneDepthParent
img All HP:0000001img Phenotypic abnormality HP:00001186img Abnormality of sulfur amino acid metabolism HP:0004339
img All HP:0000001img Phenotypic abnormality HP:00001187img Abnormality of sulfur amino acid metabolism HP:0004339
img All HP:0000001img Phenotypic abnormality HP:00001186img Abnormality of aspartate family amino acid metabolism HP:0010899
img All HP:0000001img Phenotypic abnormality HP:00001187img Abnormality of aspartate family amino acid metabolism HP:0010899
Genes (13)

Species:
human : 13
SpeciesGeneGeneIdGene NameEvidence
HumanLMBRD155788LMBR1 domain containing 1
img HP RolledUp, OMIM ID: 277380
HumanMMADHC27249methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
img HP RolledUp, OMIM ID: 277410
HumanGNMT27232glycine N-methyltransferase
img HP RolledUp, OMIM ID: 606664
HumanMMACHC25974methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
img HP RolledUp, OMIM ID: 277400
HumanSLC25A1310165solute carrier family 25 (aspartate/glutamate carrier), member 13
img HP RolledUp, OMIM ID: 605814
HumanTTC379652tetratricopeptide repeat domain 37
img HP RolledUp, OMIM ID: 222470
HumanABCD45826ATP-binding cassette, sub-family D (ALD), member 4
img HP RolledUp, OMIM ID: 614857
HumanMTRR45525-methyltetrahydrofolate-homocysteine methyltransferase reductase
img HP RolledUp, OMIM ID: 236270
HumanMTR45485-methyltetrahydrofolate-homocysteine methyltransferase
img HP RolledUp, OMIM ID: 250940
img HP RolledUp, OMIM ID: 156570
HumanMAT1A4143methionine adenosyltransferase I, alpha
img HP RolledUp, OMIM ID: 250850
HumanFAH2184fumarylacetoacetate hydrolase (fumarylacetoacetase)
img HP RolledUp, OMIM ID: 276700
HumanAHCY191adenosylhomocysteinase
img HP RolledUp, OMIM ID: 613752
img HP RolledUp, OMIM ID: 180960
HumanADK132adenosine kinase
img HP RolledUp, OMIM ID: 614300
XRefs (1)

XRef Types:
hp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
HPimg HP:0010901Abnormality of methionine metabolism0self