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Details
Link-It Detail - Human Phenotype - Abnormality of glycine metabolism
Debug Stats
  • ### Total Build Time: 32 ms 22.519 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 208 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 215 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 471 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 1.379 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 2.137 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 16.958 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.027 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Human Phenotype (1)
Abnormality of glycine metabolism HP:0010895
Definition (1)
An abnormality of a `glycine metabolic process` (GO:0006544).
Parents (1)
img Abnormality of serine family amino acid metabolism HP:0010894
Children (4)
img Hyperglycinemia HP:0002154
img Abnormality of sarcosine metabolism HP:0010898
img Hyperglycinuria HP:0003108
img Hypoglycinemia HP:0012277
Ancestral Roots
RootRoot Plus OneDepthParent
img All HP:0000001img Phenotypic abnormality HP:00001186img Abnormality of serine family amino acid metabolism HP:0010894
img All HP:0000001img Phenotypic abnormality HP:00001187img Abnormality of serine family amino acid metabolism HP:0010894
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanSLC6A19340024solute carrier family 6 (neutral amino acid transporter), member 19
img HP RolledUp, OMIM ID: 242600
img HP RolledUp, OMIM ID: 138500
HumanMMAB326625methylmalonic aciduria (cobalamin deficiency) cblB type
img HP RolledUp, OMIM ID: 251110
HumanMMAA166785methylmalonic aciduria (cobalamin deficiency) cblA type
img HP RolledUp, OMIM ID: 251100
HumanSLC36A2153201solute carrier family 36 (proton/amino acid symporter), member 2
img HP RolledUp, OMIM ID: 242600
img HP RolledUp, OMIM ID: 138500
HumanGLYCTK132158glycerate kinase
HumanMCCC264087methylcrotonoyl-CoA carboxylase 2 (beta)
img HP RolledUp, OMIM ID: 210210
HumanSLC6A2054716solute carrier family 6 (proline IMINO transporter), member 20
img HP RolledUp, OMIM ID: 242600
img HP RolledUp, OMIM ID: 138500
HumanPSAT129968phosphoserine aminotransferase 1
img HP RolledUp, OMIM ID: 610992
HumanALDH4A18659aldehyde dehydrogenase 4 family, member A1
img HP RolledUp, OMIM ID: 239510
HumanPRODH5625proline dehydrogenase (oxidase) 1
img HP RolledUp, OMIM ID: 239500
HumanPCCB5096propionyl CoA carboxylase, beta polypeptide
img HP RolledUp, OMIM ID: 606054
img HP RolledUp, OMIM ID: 232050
HumanPCCA5095propionyl CoA carboxylase, alpha polypeptide
img HP RolledUp, OMIM ID: 606054
img HP RolledUp, OMIM ID: 232000
HumanMUT4594methylmalonyl CoA mutase
img HP RolledUp, OMIM ID: 251000
HumanIVD3712isovaleryl-CoA dehydrogenase
img HP RolledUp, OMIM ID: 243500
HumanGLDC2731glycine dehydrogenase (decarboxylating)
img HP RolledUp, OMIM ID: 605899
HumanGCSH2653glycine cleavage system protein H (aminomethyl carrier)
img HP RolledUp, OMIM ID: 605899
HumanSARDH1757sarcosine dehydrogenase
img HP RolledUp, OMIM ID: 268900
HumanAMT275aminomethyltransferase
img HP RolledUp, OMIM ID: 605899
HumanACADM34acyl-CoA dehydrogenase, C-4 to C-12 straight chain
img HP RolledUp, OMIM ID: 201450
XRefs (1)

XRef Types:
hp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
HPimg HP:0010895Abnormality of glycine metabolism0self