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Details
Link-It Detail - Human Phenotype - Abnormality of neutrophils
Debug Stats
  • ### Total Build Time: 48 ms 30.229 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 201 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 341 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 448 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 2.760 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 3.021 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=22 ms Completed: 22 ms rowSize= 22.315 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.021 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Human Phenotype (1)
Abnormality of neutrophils HP:0001874
Definition (1)
Neutrophils are granular leukocytes with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
Parents (1)
img Abnormality of granulocytes HP:0001911
Children (8)
img Hypersegmentation of neutrophil nuclei HP:0004821
img Neutropenia HP:0001875
img Impaired neutrophil killing of staphylococci HP:0005512
img Reduction of neutrophil motility HP:0005400
img Abnormality of neutrophil morphology HP:0011992
img Negative nitroblue tetrazolium (NBT) reduction test HP:0003203
img Abnormal neutrophil cell number HP:0011991
img Abnormality of neutrophil physiology HP:0011990
Ancestral Roots
RootRoot Plus OneDepthParent
img All HP:0000001img Phenotypic abnormality HP:00001187img Abnormality of granulocytes HP:0001911
img All HP:0000001img Phenotypic abnormality HP:00001188img Abnormality of granulocytes HP:0001911
img All HP:0000001img Phenotypic abnormality HP:00001186img Abnormality of granulocytes HP:0001911
Genes (84)

Species:
human : 84
Page Size
Current 25
  Page 1 of 4
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNCF1653361neutrophil cytosolic factor 1
img HP RolledUp, OMIM ID: 233700
HumanMMAB326625methylmalonic aciduria (cobalamin deficiency) cblB type
img HP RolledUp, OMIM ID: 251110
HumanSUMF1285362sulfatase modifying factor 1
HumanMMAA166785methylmalonic aciduria (cobalamin deficiency) cblA type
img HP RolledUp, OMIM ID: 251100
HumanVPS13B157680vacuolar protein sorting 13 homolog B (yeast)
img HP TAS, OMIM ID: 216550
HumanNLRP3114548NLR family, pyrin domain containing 3
img HP TAS, OMIM ID: 607115
HumanDBA2114086Diamond-Blackfan anemia 2
img HP RolledUp, OMIM ID: 105650
HumanSLC46A1113235solute carrier family 46 (folate transporter), member 1
img HP RolledUp, OMIM ID: 229050
HumanG6PC392579glucose 6 phosphatase, catalytic, 3
img HP RolledUp, OMIM ID: 612541
HumanUSB179650U6 snRNA biogenesis 1
img HP RolledUp, OMIM ID: 604173
HumanLRRC8A56262leucine rich repeat containing 8 family, member A
img HP RolledUp, OMIM ID: 601495
HumanLMBRD155788LMBR1 domain containing 1
img HP RolledUp, OMIM ID: 277380
HumanSLC35C155343solute carrier family 35 (GDP-fucose transporter), member C1
img HP RolledUp, OMIM ID: 266265
HumanIRAK451135interleukin-1 receptor-associated kinase 4
img HP TAS, OMIM ID: 607676
HumanSBDS51119Shwachman-Bodian-Diamond syndrome
img HP RolledUp, OMIM ID: 260400
HumanSMARCAL150485SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
img HP RolledUp, OMIM ID: 242900
HumanICOS29851inducible T-cell co-stimulator
img HP RolledUp, OMIM ID: 607594
HumanBLNK29760B-cell linker
img HP RolledUp, OMIM ID: 613502
HumanLAMTOR228956late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
img HP RolledUp, OMIM ID: 610798
HumanTINF226277TERF1 (TRF1)-interacting nuclear factor 2
img HP TAS, OMIM ID: 268130
HumanMMACHC25974methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
img HP RolledUp, OMIM ID: 277400
HumanFTCD10841formimidoyltransferase cyclodeaminase
img HP RolledUp, OMIM ID: 229100
HumanSLC35A110559solute carrier family 35 (CMP-sialic acid transporter), member A1
img HP RolledUp, OMIM ID: 603585
HumanHAX110456HCLS1 associated protein X-1
img HP RolledUp, OMIM ID: 610738
HumanEIF2AK39451eukaryotic translation initiation factor 2-alpha kinase 3
img HP TAS, OMIM ID: 226980
XRefs (1)

XRef Types:
hp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
HPimg HP:0001874Abnormality of neutrophils0self