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Details
Link-It Detail - Human Phenotype - Abnormality of renin-angiotensin system
Debug Stats
  • ### Total Build Time: 30 ms 21.919 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 214 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 215 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 771 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.439 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 3 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 15.130 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.033 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Human Phenotype (1)
Abnormality of renin-angiotensin system HP:0000847
Definition (1)
An abnormality of the `renin-angiotensin system` (FMA:74787).
Parents (2)
img Hypertension HP:0000822
img Abnormality of the endocrine system HP:0000818
Children (4)
img Increased circulating renin level HP:0000848
img Decreased circulating aldosterone level HP:0002924
img Hyperactive renin-angiotensin system HP:0000841
img Decreased circulating renin level HP:0003351
Ancestral Roots
RootRoot Plus OneDepthParent
img All HP:0000001img Phenotypic abnormality HP:00001185img Hypertension HP:0000822
img All HP:0000001img Phenotypic abnormality HP:00001186img Hypertension HP:0000822
img All HP:0000001img Phenotypic abnormality HP:00001184img Abnormality of the endocrine system HP:0000818
Genes (16)

Species:
human : 16
SpeciesGeneGeneIdGene NameEvidence
HumanWNK465266WNK lysine deficient protein kinase 4
img HP RolledUp, OMIM ID: 601844
HumanSLC12A36559solute carrier family 12 (sodium/chloride transporter), member 3
img HP RolledUp, OMIM ID: 263800
HumanSLC12A16557solute carrier family 12 (sodium/potassium/chloride transporter), member 1
img HP RolledUp, OMIM ID: 601678
HumanSCNN1G6340sodium channel, non-voltage-gated 1, gamma subunit
img HP RolledUp, OMIM ID: 177200
img HP RolledUp, OMIM ID: 264350
HumanSCNN1B6338sodium channel, non-voltage-gated 1, beta subunit
img HP RolledUp, OMIM ID: 177200
img HP RolledUp, OMIM ID: 264350
HumanSCNN1A6337sodium channel, non-voltage-gated 1 alpha subunit
img HP RolledUp, OMIM ID: 264350
HumanNR3C24306nuclear receptor subfamily 3, group C, member 2
img HP RolledUp, OMIM ID: 177735
img HP RolledUp, OMIM ID: 605115
HumanKCNJ103766potassium inwardly-rectifying channel, subfamily J, member 10
img HP RolledUp, OMIM ID: 612780
HumanKCNJ53762potassium inwardly-rectifying channel, subfamily J, member 5
img HP RolledUp, OMIM ID: 613677
HumanKCNJ13758potassium inwardly-rectifying channel, subfamily J, member 1
img HP RolledUp, OMIM ID: 241200
HumanHSD11B23291hydroxysteroid (11-beta) dehydrogenase 2
img HP RolledUp, OMIM ID: 218030
HumanSLC26A31811solute carrier family 26 (anion exchanger), member 3
img HP RolledUp, OMIM ID: 214700
HumanCYP11B21585cytochrome P450, family 11, subfamily B, polypeptide 2
img HP RolledUp, OMIM ID: 610600
img HP RolledUp, OMIM ID: 203400
HumanCYP11B11584cytochrome P450, family 11, subfamily B, polypeptide 1
img HP RolledUp, OMIM ID: 103900
img HP RolledUp, OMIM ID: 202010
HumanCLCNKB1188chloride channel, voltage-sensitive Kb
img HP RolledUp, OMIM ID: 607364
HumanAVPR2554arginine vasopressin receptor 2
img HP RolledUp, OMIM ID: 300539
XRefs (1)

XRef Types:
hp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
HPimg HP:0000847Abnormality of renin-angiotensin system0self