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Details
Link-It Detail - Gene Ontology: Biological Processes - I-kappaB kinase/NF-kappaB cascade
Debug Stats
  • ### Total Build Time: 142 ms 37.253 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 390 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_DEFINITION gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • CONCEPT_NAMESPACE gt=0 Completed: 0 ms rowSize= 170 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 555 bytes
  • CONCEPT_CHILDREN gt=13 ms Completed: 13 ms rowSize= 2.719 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=19 ms Completed: 19 ms rowSize= 10.136 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=84 ms Completed: 84 ms rowSize= 22.029 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.136 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Gene Ontology: Biological Processes (1)
I-kappaB kinase/NF-kappaB cascade GO:0007249
Namespace (1)
biological_process
Parents (1)
img intracellular protein kinase cascade GO:0007243
Children (6)
img positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123
img regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122
img release of cytoplasmic sequestered NF-kappaB GO:0008588
img NF-kappaB import into nucleus GO:0042348
img negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124
img I-kappaB phosphorylation GO:0007252
Ancestral Roots
RootRoot Plus OneDepthParent
img biological_process GO:0008150img single-organism process GO:00446997img intracellular protein kinase cascade GO:0007243
img biological_process GO:0008150img signaling GO:00230527img intracellular protein kinase cascade GO:0007243
img biological_process GO:0008150img cellular process GO:00099877img intracellular protein kinase cascade GO:0007243
img biological_process GO:0008150img biological regulation GO:00650078img intracellular protein kinase cascade GO:0007243
img biological_process GO:0008150img regulation of biological process GO:00507897img intracellular protein kinase cascade GO:0007243
img biological_process GO:0008150img single-organism process GO:00446998img intracellular protein kinase cascade GO:0007243
img biological_process GO:0008150img cellular process GO:00099878img intracellular protein kinase cascade GO:0007243
img biological_process GO:0008150img response to stimulus GO:00508967img intracellular protein kinase cascade GO:0007243
Genes (396)

Species:
human : 221
mouse : 175
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SpeciesGeneGeneIdGene NameEvidence
MouseCcl21b100042493chemokine (C-C motif) ligand 21B (leucine)
MouseTrim5667823tripartite motif containing 5
MouseTnip3414084TNFAIP3 interacting protein 3
MouseBC031181407819cDNA sequence BC031181
MouseNlrp12378425NLR family, pyrin domain containing 12
MouseCard9332579caspase recruitment domain family, member 9
img GO ISO, Gene Ontology ID: GO:0007249
MouseZdhhc17320150zinc finger, DHHC-type containing 17
MousePlekhg5269608pleckstrin homology domain containing, family G (with RhoGef domain) member 5
MouseNlrc3268857NLR family, CARD domain containing 3
img GO ISS, Pubmed Id: 15705585, Gene Ontology ID: GO:0007249
img GO ISO, Gene Ontology ID: GO:0007249
MouseRnf31268749ring finger protein 31
MouseNod2257632nucleotide-binding oligomerization domain containing 2
MouseZdhhc13243983zinc finger, DHHC-type containing 13
MouseNfkbid243910nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
MouseMalt1240354mucosa associated lymphoid tissue lymphoma translocation gene 1
img GO RCA, Pubmed Id: 12819136, Gene Ontology ID: GO:0007249
MouseCard6239319caspase recruitment domain family, member 6
MouseAtp2c1235574ATPase, Ca++ transporting, type 2C, member 1
MouseTnip2231130TNFAIP3 interacting protein 2
img GO IDA, Pubmed Id: 11390377, Gene Ontology ID: GO:0007249
MouseIkbkap230233inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
MouseOtud7b229603OTU domain containing 7B
MouseMavs228607mitochondrial antiviral signaling protein
MouseTicam2225471toll-like receptor adaptor molecule 2
MouseNlrp3216799NLR family, pyrin domain containing 3
MouseTrim38214158tripartite motif containing 38
MouseCc2d1a212139coiled-coil and C2 domain containing 1A
MouseTifa211550TRAF-interacting protein with forkhead-associated domain
img GO IDA, Pubmed Id: 11798190, Gene Ontology ID: GO:0007249
XRefs (1)

XRef Types:
go : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
GOimg GO:0007249I-kappaB kinase/NF-kappaB cascade0self