Human | SFTPA2 | 729238 | surfactant protein A2 | The amniotic fluid concentration of SP-A decreases in spontaneous human parturition at term |
Human | GDF15 | 9518 | growth differentiation factor 15 | amniotic fluid MIC-1 is derived from the fetal membranes and decidua, but that MIC-1 is unlikely to be involved in the pathophysiology of preterm birth or premature rupture of membranes |
Human | HMGA2 | 8091 | high mobility group AT-hook 2 | Cells of the amniotic fluid strongly overexpress HMGA2 according to their fetal origin |
Human | TTR | 7276 | transthyretin | results show that transthyretin is present in amniotic fluid of preeclamptic & control women as a mixture of dimeric & post-translationally modified monomeric forms; preeclamptic women showed a significant increase in the amount of monomeric proteins |
Human | TNFRSF1B | 7133 | tumor necrosis factor receptor superfamily, member 1B | amniotic fluid TNF-alpha and soluble TNF receptor concentration regulation is affected by race and preterm birth |
Human | TNFRSF1A | 7132 | tumor necrosis factor receptor superfamily, member 1A | amniotic fluid TNF-alpha and soluble TNF receptor concentration regulation is affected by race and preterm birth amniotic fluid sTNF-R1 levels did not differ significantly before and after labor |
Human | TNF | 7124 | tumor necrosis factor | amniotic fluid TNF-alpha and soluble TNF receptor concentration regulation is affected by race and preterm birth Amniotic fluid TNF-alpha may promote the onset of labor at term and/or term labor contributing to subsequent delivery may induce the production and secretion of TNF-alpha into the amniotic cavity In blacks we detected a significant association between higher amniotic fluid concentrations of TNFalpha and preterm birth this may be indicative of a TNF-alpha mediated pathological process of preterm birth in blacks but not in whites |
Human | SFTPB | 6439 | surfactant protein B | Intra-amniotic infection was associated with an increased amniotic fluid concentration of SP-B in patients who received antenatal corticosteroids within 7 days prior to amniocentesis no significant difference in the median amniotic fluid SP-B concentrations between women in labor and those not in labor |
Human | CX3CL1 | 6376 | chemokine (C-X3-C motif) ligand 1 | It is present, and its gene expressed, in amniotic fluid during pregnancy |
Human | S100B | 6285 | S100 calcium binding protein B | Results in high-risk pregnancies demonstrated that S100B concentration increased in amniotic fluid and in cord blood of fetuses with brain damage [review] An elevated concentration of amniotic fluid S100B may reflect intra-amniotic infection/inflammation and not necessarily fetal neurologic damage |
Human | S100A7 | 6278 | S100 calcium binding protein A7 | Psoriasin present in the amniotic fluid might have consequential immunobiological effects during the fetal development |
Human | SERPINB2 | 5055 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | in patients with complex congenital malformations amniotic fluid levels of plasminogen activator inhibitor type 2(PAI2) |
Human | NPPB | 4879 | natriuretic peptide B | data suggest that amniotic fluid concentrations of human brain natriuretic peptide and endothelin-1 were highest in the twins with polyhydramnios and lowest in oligohydramnios, suggesting their importance in the regulation of amniotic fluid volume |
Human | LEP | 3952 | leptin | ratios of amniotic fluid leptin levels to maternal serum leptin levels were elevated in preeclamptic women |
Human | INSL3 | 3640 | insulin-like 3 (Leydig cell) | INSL3 is clearly present in human male amniotic fluid in the second trimester, where abdominal testis translocation takes place INSL3 concentration in human amniotic fluid is potentially predictive of fetal sex and pre-eclampsia, and presumably reflects the functioning of the fetal Leydig cell population |
Human | IL6 | 3569 | interleukin 6 (interferon, beta 2) | Amniotic fluid interleukin-6 is increased in patients with cervical incompetence |
Human | IGFBP3 | 3486 | insulin-like growth factor binding protein 3 | IGF BP3 was associated with birth weight as measured in seconsd semestser amniotic fluid |
Human | IGFBP1 | 3484 | insulin-like growth factor binding protein 1 | IGF BP1 was associated with lower birth weight as measured in seconsd semestser amniotic fluid |
Human | IGF2 | 3481 | insulin-like growth factor 2 (somatomedin A) | IGF II is an early indicators of fetal growth as measured in seconsd semestser amniotic fluid |
Human | EPO | 2056 | erythropoietin | Prenatal high amniotic fluid erythropoietin levels can identify type 1 diabetic pregnancies at increased risk of severe perinatal complications |
Human | EDN1 | 1906 | endothelin 1 | The amniotic fluid concentration of ET1 is elevated by the second trimester in women who later develop intrauterine growth restriction data suggest that amniotic fluid concentrations of human brain natriuretic peptide and endothelin-1 were highest in the twins with polyhydramnios and lowest in oligohydramnios, suggesting their importance in the regulation of amniotic fluid vo |
Human | DAZL | 1618 | deleted in azoospermia-like | Our results suggest that human amniotic fluid represents a new source for the isolation of human DAZL-, C-kit-, SSEA-4-, and Oct-4-positive stem cells without raising the ethical issues associated with human embryonic research |
Human | CGB | 1082 | chorionic gonadotropin, beta polypeptide | in patients with complex congenital malformations amniotic fluid levels of beta-hCG were higher than in controls |
Human | AQP9 | 366 | aquaporin 9 | The APQ9 mRNA expression in fetal membranes suggest that APQ9 may be an important water channel in intramembranous amniotic fluid water regulation |
Human | FAS | 355 | Fas cell surface death receptor | maternal serum sFas antigen decreased significantly in the first trimester of pregnancy and at term, possibly affecting immune tolerance and apoptosis for rupture of membranes; amniotic fluid sFas decreased at term compared with the second trimester |