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Genes (15)
Species: human : 15 | |
Human | TP53 | 7157 | tumor protein p53 | Title:[Association between Bam HI RFLP p53 gene polymorphism and brain infarction volume in patients with atherothrombotic ischemic stroke]|Association:Y|Conclusion:A significant association between p53 Bam HI polymorphism and infarction volume in patients with carotid atherothrombotic stroke confirms an important role of apoptosis in ischemic brain lesions formation that demands temporary antiapoptotic influence on patients with stroke. | Human | PTGS2 | 5743 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | prostaglandin-endoperoxide synthase 2 polymorphisms, prostaglandin-E receptor 2 polymorphisms, and C-reactive protein concentrations may have a role in atherothrombosis | Human | PTGER2 | 5732 | prostaglandin E receptor 2 (subtype EP2), 53kDa | prostaglandin-endoperoxide synthase 2 polymorphisms, prostaglandin-E receptor 2 polymorphisms, and C-reactive protein concentrations may have a role in atherothrombosis | Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | discussion of the role of PAI-1 in atherothrombosis [review] | Human | HLA-DRB1 | 3123 | | Title:The Fc gammaRIIa polymorphism R/H131, autoantibodies against the platelet receptors GPIb alpha and Fc gammaRIIa and a risk for thromboembolism in lupus anticoagulant patients.|Association:Not Found|Conclusion:There was no correlation between the presence of anti-FcgammaRIIa or anti-GPIbalpha autoantibodies and the FcgammaRIIa -R/H131 polymorphism, nor the incidence of TE, nor HLA class II alleles. | Human | HLA-DQB1 | 3119 | | Title:The Fc gammaRIIa polymorphism R/H131, autoantibodies against the platelet receptors GPIb alpha and Fc gammaRIIa and a risk for thromboembolism in lupus anticoagulant patients.|Association:Not Found|Conclusion:There was no correlation between the presence of anti-FcgammaRIIa or anti-GPIbalpha autoantibodies and the FcgammaRIIa -R/H131 polymorphism, nor the incidence of TE, nor HLA class II alleles. | Human | HLA-DQA1 | 3117 | | Title:The Fc gammaRIIa polymorphism R/H131, autoantibodies against the platelet receptors GPIb alpha and Fc gammaRIIa and a risk for thromboembolism in lupus anticoagulant patients.|Association:Not Found|Conclusion:There was no correlation between the presence of anti-FcgammaRIIa or anti-GPIbalpha autoantibodies and the FcgammaRIIa -R/H131 polymorphism, nor the incidence of TE, nor HLA class II alleles. | Human | GAS6 | 2621 | growth arrest-specific 6 | Title:Human vitamin K-dependent GAS6: gene structure,allelic variation, and association with stroke.|Association:Not Found|Conclusion:The SNP identification in GAS6 reported here would be very useful in future association studies aimed at determining the physiologic role of GAS6 in stroke and other human diseases. | Human | FN1 | 2335 | fibronectin 1 | elevated plasma fibronectin levels are associated with venous thromboembolism (VTE) especially in males, and extend the potential association between biomarkers and risk factors for arterial atherothrombosis and VTE | Human | FGB | 2244 | fibrinogen beta chain | Title:[Relationship between fibrinogen B beta gene FGB -455G/A polymorphism and atherosclerotic cerebral infarction]|Association:Y|Conclusion:The study demonstrates that A allele of the B beta gene FGB -455G/A polymorphism may be a susceptible predictor of the occurrence of ACI, particularly in smokers. | Human | FCGR2A | 2212 | Fc fragment of IgG, low affinity IIa, receptor (CD32) | Title:The Fc gammaRIIa polymorphism R/H131, autoantibodies against the platelet receptors GPIb alpha and Fc gammaRIIa and a risk for thromboembolism in lupus anticoagulant patients.|Association:Not Found|Conclusion:There was no correlation between the presence of anti-FcgammaRIIa or anti-GPIbalpha autoantibodies and the FcgammaRIIa -R/H131 polymorphism, nor the incidence of TE, nor HLA class II alleles. | Human | F12 | 2161 | coagulation factor XII (Hageman factor) | Title:Rapid detection of the 46C --> T polymorphism in the factor XII gene, a novel genetic risk factor for thrombosis, by melting peak analysis using fluorescence hybridization probes.|Association:Not Found|Conclusion:In conclusion, the technique presented allows for easy, reliable, and rapid detection of this polymorphism, and is suitable for typing both small and large numbers of DNA samples. | Human | CYBA | 1535 | cytochrome b-245, alpha polypeptide | Title:Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction.|Association:Not Found|Conclusion:We conclude that C242T of p22(phox) gene is not involved in thrombotic cerebral infarction but more likely in increased NAD(P)H oxidase activity in phagocytes. | Human | CRP | 1401 | C-reactive protein, pentraxin-related | Increased CRP levels are associated with atherothrombosis Transgenic human CRP is not pro-atherogenic, pro-atherothrombotic or pro-inflammatory in apoE-/- mice prostaglandin-endoperoxide synthase 2 polymorphisms, prostaglandin-E receptor 2 polymorphisms, and C-reactive protein concentrations may have a role in atherothrombosis CRP is a procoagulant and has implications for atherothrombosis | Human | CD36 | 948 | CD36 molecule (thrombospondin receptor) | data suggest that platelet Cd36 has a key role in VLDL-induced collagen-mediated platelet aggregation, possibly contributing to atherothrombosis associated with increased VLDL levels |
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