Human | OB4 | 404683 | Obesity, susceptibility to, on chromosome 4 | |
Human | OB10Q | 353126 | Obesity, susceptibility to, on chromosome 10q | |
Human | ANKK1 | 255239 | ankyrin repeat and kinase domain containing 1 | APM linkage analysis suggested that the DD2R gene TaqI polymorphism had evidence of linkage with blood pressure, as well as with obesity |
Human | BBS12 | 166379 | Bardet-Biedl syndrome 12 | |
Human | CCDC80 | 151887 | coiled-coil domain containing 80 | In conclusion, the expression pattern of URB suggests its role in obesity and the results suggest that URB is secreted, at least in part, from adipocytes |
Human | PTPRVP | 148713 | protein tyrosine phosphatase, receptor type, V, pseudogene | Transgenic mice lacking protein tyrosine phosphatase OST-PTP are hypoglycemic and are protected from obesity and glucose intolerance because of an increase in islet beta-cell proliferation, insulin secretion, and insulin sensitivity |
Human | SERPINA12 | 145264 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 | Induction of human vaspin mRNA expression in adipose tissue is regulated in a fat depot-specific manner and could be associated with parameters of obesity, insulin resistance, and glucose metabolism |
Human | GPR119 | 139760 | G protein-coupled receptor 119 | GPR119 therefore represents a novel and attractive potential target for the therapy of obesity and related metabolic disorders |
Human | PPARGC1B | 133522 | peroxisome proliferator-activated receptor gamma, coactivator 1 beta | Variation of PGC-1beta may contribute to the pathogenesis of obesity, with a widespread Ala203 allele being a risk factor for the development of this common disorder Recent studies have elucidated the function of the PGC-1 coactivators in different tissues and have highlighted the implications of PGC-1 dysregulation in diseases such as diabetes, obesity, cardiomyopathy, or neurodegeneration |
Human | BBS5 | 129880 | Bardet-Biedl syndrome 5 | |
Human | TTC8 | 123016 | tetratricopeptide repeat domain 8 | |
Human | APOA5 | 116519 | apolipoprotein A-V | Title:Further evidence for the association between obesity-related traits and the apolipoprotein A-IV gene.|Association:Y|Conclusion:Our data suggest that the APOA-IV gene polymorphisms investigated are associated with obesity-related traits. The effects of X*2 and 347Ser variants on BMI and the 360His variant on waist circumference depended on smoking status. the APOA5-1131T>C SNP, which is present in approximately 13% of this population, modulates the effect of fat intake on BMI and obesity risk in both men and women |
Human | TMEM67 | 91147 | transmembrane protein 67 | |
Human | DGAT2 | 84649 | diacylglycerol O-acyltransferase 2 | our results do not support the hypothesis of an important role of common genetic variation in DGAT2 for the development of obesity |
Human | MCHR2 | 84539 | melanin-concentrating hormone receptor 2 | MCHR2 is not a major contributor to polygenic obesity |
Human | ARL6 | 84100 | ADP-ribosylation factor-like 6 | |
Human | USP26 | 83844 | ubiquitin specific peptidase 26 | |
Human | PNPLA3 | 80339 | patatin-like phospholipase domain containing 3 | association between PNPLA3 and obesity; the rs738409 variant was associated with insulin secretion |
Human | CEP290 | 80184 | centrosomal protein 290kDa | |
Human | ASAM | 79827 | | We identified ACAM (adipocyte adhesion molecule), a novel homologue of the CTX (cortical thymocyte marker in Xenopus) gene family, which may be the critical adhesion molecule in adipocyte differentiation and development of obesity |
Human | EHMT1 | 79813 | euchromatic histone-lysine N-methyltransferase 1 | |
Human | BBS10 | 79738 | Bardet-Biedl syndrome 10 | |
Human | STEAP4 | 79689 | STEAP family member 4 | Human WAT STAMP2 associates with obesity and insulin resistance independently of adiponectin |
Human | ADIPOR2 | 79602 | adiponectin receptor 2 | may contribute to the molecular association between obesity and prostate cancer through a complex interaction with other hormones and cytokines that also play important roles in the pathophysiology of obesity and prostate cancer |
Human | FTO | 79068 | fat mass and obesity associated | Click here to display 17 evidence detail records. |